Standard Oligonucleotide Modifications for custom DNA and RNA synthesis
Eurofins Genomics offers a wide variety of modifications for both DNA and RNA oligos to meet the needs of virtually any project. Modifications that are regularly stocked in-house are considered the "standard modifications portfolio." Standard modifications are listed below.
Non-standard modifications
Non-standard modifications refer to any modification that is not listed in the standard portfolio. Typically, non-standard modifications derive from a.) custom modifications supplied by the customer, b.) special requests from customers for modifications not listed in the standard portfolio, and c.) modifications that we have prior expertise with but may not keep in stock due to the infrequency of orders. Eurofins Genomics can accommodate requests for non-standard modifications. We understand that much of science revolves around experimentation and new needs arise from new techniques. Do not see a modification you want? Contact us to request a modification.
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Fluorophores
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Pricing
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Additional Information
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Modification
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Designator
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Positions allowed
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Max Em (nm)
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25 nmole price
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50 nmole price
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250 nmole price
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1 µmole price
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2 µmole price
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5 µmole price
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10 µmole price
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Extinction coefficient (M-1cm–1)
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Max Abs (nm)
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DNA or RNA
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Tubes or Plates
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Standard or
non-std
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Notes
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Alexa Fluor 350 (NHS Ester)
|
[Alexa350]
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5', 3'
|
424
|
|
|
$692.18
|
$692.18
|
$1,787.16
|
$2,940.44
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$7,351.10
|
|
|
19000
|
346
|
DNA
|
T
|
Std
|
|
| |
CF 405S succinimidyl ester (CF405SN) (NHS Ester)
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[CF405SN]
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5', 3'
|
431
|
|
|
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$278.78
|
$1,250.80
|
|
|
|
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33000
|
404
|
DNA
|
T
|
Std
|
|
| |
Tide Fluor 1
|
[TF1]
|
5', 3', Int
|
447
|
|
|
$148.40
|
$148.40
|
$262.88
|
$339.20
|
$848.00
|
$1,454.32
|
|
|
341
|
DNA
|
T
|
Std
|
|
| |
ATTO 390 (NHS Ester
|
[ATTO390]
|
5', 3'
|
479
|
|
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$161.12
|
$234.26
|
$323.30
|
$584.06
|
$1,535.68
|
|
|
24000
|
390
|
DNA
|
T
|
Std
|
|
| |
5-FAM
|
[5FAM]
|
5'
|
518
|
|
|
$58.30
|
$74.20
|
$153.70
|
$167.48
|
$243.80
|
$556.50
|
|
|
492
|
Both
|
T
|
Std
|
|
| |
Alexa Fluor 488 (NHS ester)
|
[Alexa488]
|
5', 3'
|
519
|
|
|
$318.00
|
$318.00
|
$477.00
|
$539.54
|
$824.73
|
|
|
71000
|
496
|
DNA
|
T
|
Std
|
|
| |
Fluorescein
|
[FL]
|
5', Int
|
520
|
|
|
$68.90
|
$85.86
|
$185.50
|
$262.88
|
$479.12
|
|
|
83000
|
495
|
DNA
|
T
|
Std
|
|
| |
6-FAM
|
[FAM]
|
5', 3'
|
521
|
|
|
$72.08
|
$90.10
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$195.04
|
$253.34
|
$362.52
|
$556.50
|
|
75000
|
495
|
Both
|
Both
|
Std
|
|
| |
Fluorescein dT
|
[FLUdT]
|
5', Int
|
522
|
|
|
$212.00
|
$238.50
|
$339.20
|
$380.65
|
$727.05
|
$1,696.00
|
|
75000
|
494
|
DNA
|
T
|
Std
|
|
| |
Tide Fluor 2
|
[TF2]
|
5', 3', Int
|
522
|
|
|
$148.40
|
$148.40
|
$262.88
|
$339.20
|
$848.00
|
$984.74
|
|
|
499
|
DNA
|
T
|
Std
|
|
| |
ATTO 488 (NHS Ester)
|
[ATTO488]
|
5', 3'
|
523
|
|
|
$217.30
|
$289.38
|
$400.68
|
$495.44
|
$761.29
|
|
|
90000
|
501
|
DNA
|
T
|
Std
|
|
| |
Oregon Green 488
|
[OG488]
|
5', 3', Int
|
524
|
|
|
$397.50
|
$397.50
|
$598.90
|
$676.70
|
$1,037.21
|
$6,095.00
|
|
76000
|
496
|
DNA
|
T
|
Std
|
|
| |
TET
|
[TET]
|
5'
|
539
|
|
|
$79.50
|
$99.64
|
$201.40
|
$402.80
|
$1,007.00
|
$795.00
|
|
86000
|
519
|
Both
|
Both
|
Std
|
|
| |
VIC
|
[VIC]
|
5'
|
543
|
|
|
$185.00
|
$185.00
|
$205.00
|
$360.00
|
$699.00
|
$1,199.00
|
|
|
526
|
DNA
|
T
|
Std
|
|
| |
CAL Fluor Gold 540
|
[CalFluor540]
|
5'
|
543
|
|
|
$397.50
|
$397.50
|
$598.90
|
$676.70
|
$1,037.21
|
$6,095.00
|
|
81100
|
522
|
DNA
|
T
|
Std
|
|
| |
JOE
|
[JOE]
|
5', 3', Int
|
548
|
|
|
$217.30
|
$217.30
|
$328.60
|
$0.00
|
$0.00
|
$7,844.00
|
|
73000
|
520
|
DNA
|
T
|
Std
|
|
| |
Yakima Yellow
|
[YAKYE]
|
5'
|
549
|
|
|
$83.74
|
$106.00
|
$213.48
|
$280.90
|
$561.80
|
$1,123.60
|
|
|
530
|
DNA
|
T
|
Std
|
|
| |
Alexa Fluor 532 (NHS Ester)
|
[Alexa532]
|
5', 3'ATTO 532
|
553
|
|
|
$397.50
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$397.50
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$598.90
|
$676.70
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$1,037.21
|
$6,095.00
|
|
81000
|
532
|
DNA
|
T
|
Std
|
|
| |
ATTO 532 (NHS Ester)
|
[ATTO532]
|
5', 3'
|
553
|
|
|
$217.30
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$289.38
|
$400.68
|
$497.46
|
$761.29
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|
|
115000
|
532
|
DNA
|
T
|
Std
|
|
| |
HEX
|
[HEX]
|
5'
|
556
|
|
|
$79.50
|
$99.64
|
$201.40
|
$227.58
|
$344.39
|
$723.98
|
|
96000
|
537
|
Both
|
Both
|
Std
|
|
| |
Cyanine3
|
[Cy3]
|
5', Int
|
563
|
|
|
$119.10
|
$150.30
|
$233.70
|
$286.20
|
$480.00
|
$880.00
|
|
150000
|
550
|
DNA
|
T
|
Std
|
|
| |
Cyanine3 (NHS Ester)
|
[Cy3es]
|
5'
|
563
|
|
|
$119.10
|
$150.30
|
$233.70
|
$286.20
|
$480.00
|
$880.00
|
|
150000
|
550
|
DNA
|
T
|
Non
|
|
| |
Alexa Fluor 555 (NHS Ester)
|
[Alexa555]
|
5', 3'
|
565
|
|
|
$692.18
|
$692.18
|
$1,787.16
|
$2,940.44
|
$7,351.10
|
|
|
150000
|
555
|
DNA
|
T
|
Std
|
|
| |
Alexa Fluor 546 (NHS Ester)
|
[Alexa546]
|
5', 3'
|
573
|
|
|
$397.50
|
$397.50
|
$598.90
|
$671.67
|
$1,037.21
|
$6,095.00
|
|
104000
|
556
|
DNA
|
T
|
Std
|
|
| |
ATTO 550 (NHS Ester)
|
[ATTO550]
|
5', 3'
|
576
|
|
|
$217.30
|
$289.38
|
$400.68
|
$495.44
|
$761.29
|
|
|
120000
|
554
|
DNA
|
T
|
Std
|
|
| |
TAMRA dT
|
[TAMdT]
|
5', Int
|
576
|
|
|
$165.36
|
$299.98
|
$447.32
|
$735.11
|
$1,837.78
|
|
|
90000
|
544
|
DNA
|
T
|
Std
|
|
| |
Tide Fluor 3
|
[TF3]
|
5', 3', Int
|
578
|
|
|
$148.40
|
$148.40
|
$262.88
|
$339.20
|
$848.00
|
$984.74
|
|
|
554
|
DNA
|
T
|
Std
|
|
| |
TAMRA
|
[TAM]
|
3'
|
580
|
|
|
$103.88
|
$121.90
|
$185.50
|
$206.44
|
$317.21
|
$826.80
|
|
89000
|
556
|
DNA
|
Both
|
Std
|
|
| |
5-Tamra (NHS Ester)
|
[TMR5]
|
5'
|
583
|
|
|
$137.80
|
$164.30
|
$265.00
|
$296.06
|
$782.44
|
$1,802.00
|
|
|
557
|
DNA
|
T
|
Std
|
|
| |
CAL Fluor 590
|
[CalFluor590]
|
5'
|
591
|
|
|
$371.00
|
$371.00
|
$482.30
|
$917.43
|
$2,290.93
|
$3,858.40
|
|
79000
|
569
|
DNA
|
T
|
Std
|
|
| |
ATTO 565 (NHS Ester)
|
[ATTO565]
|
5', 3'
|
592
|
|
|
$184.44
|
$278.78
|
$373.12
|
$461.21
|
$708.93
|
|
|
120000
|
563
|
DNA
|
T
|
Std
|
|
| |
ROX (NHS Ester)
|
[ROX]
|
5', 3'
|
602
|
|
|
$184.44
|
$184.44
|
$278.78
|
$344.39
|
$528.68
|
$1,897.40
|
|
82000
|
575
|
DNA
|
T
|
Std
|
|
| |
Alexa Fluor 568 (NHS Ester)
|
[Alexa568]
|
5', 3'
|
603
|
|
|
$692.18
|
$692.18
|
$1,787.16
|
$2,940.44
|
$7,351.10
|
|
|
91000
|
578
|
DNA
|
T
|
Std
|
|
| |
Texas Red (NHS Ester)
|
[TxRed]
|
5', 3'
|
603
|
|
|
$212.00
|
$256.52
|
$367.82
|
$453.95
|
$697.85
|
|
|
116000
|
583
|
DNA
|
T
|
Std
|
|
| |
Cyanine3.5
|
[Cy35]
|
5', Int
|
604
|
|
|
$183.38
|
$196.10
|
$311.64
|
$564.45
|
$1,409.80
|
|
|
116000
|
591
|
DNA
|
T
|
Std
|
|
| |
CAL Fluor Red 610
|
[CalFluor610]
|
5'
|
610
|
|
|
$371.00
|
$371.00
|
$482.30
|
$917.43
|
$2,290.93
|
$3,858.40
|
|
108000
|
590
|
DNA
|
T
|
Std
|
|
| |
Tide Fluor 4
|
[TF4]
|
5', 3', Int
|
610
|
|
|
$148.40
|
$148.40
|
$262.88
|
$339.20
|
$848.00
|
$984.74
|
|
|
588
|
DNA
|
T
|
Std
|
|
| |
Alexa Fluor 594 (NHS Ester)
|
[Alexa594]
|
5', 3'
|
617
|
|
|
$466.40
|
$466.40
|
$710.20
|
$798.55
|
$2,647.88
|
$6,837.00
|
|
73000
|
590
|
DNA
|
T
|
Std
|
|
| |
ATTO 590 (NHS Ester)
|
[ATTO590]
|
5', 3'
|
624
|
|
|
$184.44
|
$278.78
|
$373.12
|
$460.20
|
$708.93
|
|
|
120000
|
594
|
DNA
|
T
|
Std
|
|
| |
Alexa Fluor 633 (NHS Ester)
|
[Alexa633]
|
5', 3'
|
647
|
|
|
$692.18
|
$692.18
|
$1,787.16
|
$2,940.44
|
$7,351.10
|
|
|
239000
|
632
|
DNA
|
T
|
Std
|
|
| |
ATTO 633 (NHS Ester)
|
[ATTO633]
|
5', 3'
|
657
|
|
|
$217.30
|
$289.38
|
$400.68
|
$495.44
|
$761.29
|
|
|
130000
|
629
|
DNA
|
T
|
Std
|
|
| |
Cyanine5
|
[Cy5]
|
5'
|
662
|
|
|
$217.30
|
$289.38
|
$400.68
|
$495.44
|
$761.29
|
|
|
130000
|
629
|
DNA
|
T
|
Std
|
|
| |
Cyanine5 (NHS Ester)
|
[Cy5es]
|
5'
|
662
|
|
|
$113.42
|
$143.10
|
$222.60
|
$247.72
|
$518.61
|
$1,378.00
|
|
250000
|
646
|
Both
|
T
|
Std
|
|
| |
Alexa Fluor 647 (NHS Ester)(NHS Ester)
|
[Alexa647]
|
5', 3'
|
665
|
|
|
$318.00
|
$318.00
|
$477.00
|
$534.72
|
$824.73
|
|
|
239000
|
650
|
DNA
|
T
|
Std
|
|
| |
ATTO 647N (NHS Ester)
|
[ATTO647N]
|
5', 3'
|
669
|
|
|
$217.30
|
$289.38
|
$400.68
|
$495.44
|
$761.29
|
|
|
150000
|
644
|
DNA
|
T
|
Std
|
|
| |
Tide Fluor 5 (NHS Ester)
|
[TF5]
|
5', 3'
|
670
|
|
|
$148.40
|
$148.40
|
$262.88
|
$339.20
|
$848.00
|
$984.74
|
|
|
656
|
DNA
|
T
|
Std
|
|
| |
ATTO 655 (NHS Ester)
|
[ATTO655]
|
5', 3'
|
684
|
|
|
$161.12
|
$234.26
|
$323.30
|
$614.27
|
$1,535.68
|
|
|
125000
|
663
|
DNA
|
T
|
Std
|
|
| |
Alexa Fluor 660 (NHS Ester)
|
[Alexa660]
|
5', 3'
|
690
|
|
|
$466.40
|
$466.40
|
$710.20
|
$798.55
|
$1,223.51
|
$6,837.00
|
|
132000
|
663
|
DNA
|
T
|
Std
|
|
| |
ATTO 680 (NHS Ester)
|
[ATTO680]
|
5'
|
698
|
|
|
$217.30
|
$289.38
|
$400.68
|
$521.52
|
$1,616.50
|
|
|
125000
|
680
|
DNA
|
T
|
Std
|
|
| |
Alexa Fluor 680 (NHS Ester) (NHS Ester)
|
[Alexa680]
|
5', 3'
|
702
|
|
|
$692.18
|
$692.18
|
$1,787.16
|
$2,940.44
|
$7,351.10
|
|
|
184000
|
679
|
DNA
|
T
|
Std
|
|
| |
Tide Fluor 6
|
[TF6]
|
5', 3', Int
|
702
|
|
|
$148.40
|
$148.40
|
$262.88
|
$339.20
|
$848.00
|
$984.74
|
|
|
686
|
DNA
|
T
|
Std
|
|
| |
Cyanine5.5
|
[Cy55]
|
5'
|
707
|
|
|
$195.04
|
$217.30
|
$328.60
|
$312.17
|
$624.34
|
$3,286.00
|
|
209000
|
688
|
DNA
|
T
|
Std
|
|
| |
ATTO 700 (NHS Ester)
|
[ATTO700]
|
5', 3'
|
719
|
|
|
$161.12
|
$234.26
|
$323.30
|
$614.27
|
$1,535.68
|
|
|
120000
|
700
|
DNA
|
T
|
Std
|
|
| |
Alexa Fluor 700 (NHS Ester)
|
[Alexa700]
|
5', 3'
|
723
|
|
|
$692.18
|
$692.18
|
$1,787.16
|
$2,940.44
|
$7,351.10
|
|
|
192000
|
702
|
DNA
|
T
|
Std
|
|
| |
ATTO 740 (NHS Ester)
|
[ATTO740]
|
5', 3'
|
764
|
|
|
$153.70
|
$222.60
|
$307.40
|
|
|
|
|
120000
|
740
|
DNA
|
T
|
Std
|
|
| |
Alexa Fluor 750 (NHS Ester)
|
[Alexa750]
|
5', 3'
|
775
|
|
|
$466.40
|
$466.40
|
$710.20
|
$798.55
|
$1,223.51
|
|
|
240000
|
749
|
DNA
|
T
|
Std
|
|
| |
Tide Fluor 7
|
[TF7]
|
5', 3', Int
|
775
|
|
|
$148.40
|
$148.40
|
$262.88
|
$339.20
|
$848.00
|
$984.74
|
|
|
756
|
DNA
|
T
|
Std
|
|
| |
Tide Fluor 8
|
[TF8]
|
5', 3', Int
|
808
|
|
|
$148.40
|
$148.40
|
$262.88
|
$339.20
|
$848.00
|
$984.74
|
|
|
787
|
DNA
|
T
|
Std
|
|
| |
Quenchers
|
|
Pricing
|
|
Additional Information
|
| |
Modification
|
Designator
|
Positions allowed
|
N/A
|
|
25 nmole price
|
50 nmole price
|
250 nmole price
|
1 µmole price
|
2 µmole price
|
5 µmole price
|
10 µmole price
|
|
Extinction coefficient (M-1cm–1)
|
Max Abs (nm)
|
DNA or RNA
|
Tubes or Plates
|
Std or non-std
|
Notes
|
| |
BBQ650
|
[BBQ650]
|
5', 3'
|
|
|
|
$272.69
|
$272.69
|
$311.64
|
$623.28
|
$1,558.20
|
|
|
33000
|
650
|
DNA
|
T
|
Std
|
|
| |
BHQ1
|
[BHQ1]
|
5', 3'
|
|
|
|
$116.60
|
$153.70
|
$222.60
|
$380.65
|
$1,065.30
|
$2,120.00
|
|
34000
|
534
|
DNA
|
T
|
Std
|
|
| |
BHQ1 dT
|
[BHQ1dT]
|
5', Int
|
|
|
|
|
$172.78
|
$267.12
|
$508.80
|
$1,272.00
|
|
|
34000
|
534
|
DNA
|
T
|
Std
|
|
| |
BHQ2
|
[BHQ2]
|
5', 3'
|
|
|
|
$116.60
|
$153.70
|
$222.60
|
$287.00
|
$380.65
|
$2,120.00
|
|
91000
|
579
|
DNA
|
T
|
Std
|
|
| |
BHQ2 dT
|
[BHQ2dT]
|
5', Int
|
|
|
|
|
$294.68
|
$405.98
|
$735.11
|
$1,837.78
|
|
|
91000
|
579
|
DNA
|
T
|
Std
|
|
| |
Dabcyl (standard)
|
[DAB}
|
3'
|
|
|
|
$97.52
|
$121.90
|
$185.50
|
$206.44
|
$396.76
|
$916.90
|
|
32000
|
453
|
DNA
|
T
|
Std
|
|
| |
Dabcyl dT
|
[DABdT]
|
5', Int
|
|
|
|
$302.10
|
$405.45
|
$405.45
|
$731.40
|
$1,828.50
|
|
|
32000
|
478
|
DNA
|
T
|
Std
|
|
| |
TAMRA
|
[TAM]
|
5', 3'
|
|
|
|
$103.88
|
$121.90
|
$185.50
|
$206.44
|
$317.21
|
$826.80
|
|
91000
|
557
|
DNA
|
T
|
Std
|
|
| |
Tide Quencher 1
|
[TQ1]
|
3'
|
|
|
|
$48.76
|
$61.48
|
$122.96
|
$212.00
|
$397.50
|
$673.10
|
|
20000
|
490
|
DNA
|
T
|
Std
|
|
| |
Tide Quencher 2
|
[TQ2]
|
3'
|
|
|
|
$48.76
|
$61.48
|
$122.96
|
$212.00
|
$397.50
|
$673.10
|
|
21000
|
515
|
DNA
|
T
|
Std
|
|
| |
Tide Quencher 3
|
[TQ3]
|
3'
|
|
|
|
$48.76
|
$61.48
|
$122.96
|
$212.00
|
$397.50
|
$673.10
|
|
22000
|
570
|
DNA
|
T
|
Std
|
|
| |
Tide Quencher 5
|
[TQ5]
|
3'
|
|
|
|
$48.76
|
$61.48
|
$122.96
|
$212.00
|
$397.50
|
$673.10
|
|
24000
|
670
|
DNA
|
T
|
Std
|
|
| |
Attachment Linker Mods
|
|
Pricing
|
|
Additional Information
|
| |
Modification
|
Designator
|
Positions allowed
|
N/A
|
|
25 nmole
|
50 nmole
|
250 nmole
|
1 µmole
|
2 µmole
|
5 µmole
|
10 µmole
|
|
N/A
|
N/A
|
DNA or RNA
|
Tubes or Plates
|
Std or non-std
|
Notes
|
| |
Amino Modifier C12
|
[AmC12]
|
5'
|
|
|
$66.78
|
$66.78
|
$85.86
|
$127.20
|
$145.01
|
$222.55
|
$514.10
|
|
|
|
DNA
|
Both
|
Std
|
|
| |
Amino Modifier C3
|
[AmC3]
|
5', 3'
|
|
|
|
$111.30
|
$111.30
|
$155.82
|
$281.96
|
$704.90
|
|
|
|
|
DNA
|
T
|
Std
|
|
| |
Amino Modifier C6
|
[AmC6]
|
5'
|
|
|
$15.90
|
$29.68
|
$39.22
|
$66.78
|
$74.52
|
$201.40
|
$243.80
|
|
|
|
Both
|
Both
|
Std
|
|
| |
Amino Modifier C6-dT
|
[AmC6dT]
|
5', Int
|
|
|
|
$138.86
|
$167.48
|
$251.22
|
$310.16
|
$476.31
|
$1,001.70
|
|
|
|
Both
|
Both
|
Std
|
|
| |
Amino Modifier C7
|
[AmC7]
|
Int, 3'
|
|
|
|
$26.50
|
$26.50
|
$42.40
|
$80.56
|
$201.40
|
$265.00
|
|
|
|
Both
|
Both
|
Std
|
|
| |
Uni-Link AminoModifier
|
[AmUni]
|
5', Int
|
|
|
|
$83.74
|
$106.00
|
$161.12
|
$201.40
|
$307.14
|
$645.54
|
|
|
|
DNA
|
Both
|
Std
|
|
| |
i3Thiodl
|
[i3Thiodl]
|
5', Int
|
|
|
|
|
$278.78
|
$1,250.80
|
|
|
|
|
|
|
DNA
|
T
|
Std
|
|
| |
Thiol Modifier C6 S-S
|
[ThiolC6]
|
5', Int
|
|
|
|
$153.70
|
$153.70
|
$238.50
|
$477.00
|
$1,192.50
|
$916.90
|
|
|
|
DNA
|
T
|
Std
|
|
| |
Thiol Mod C3 S-S
|
[ThiolC3]
|
3'
|
|
|
|
$121.90
|
$121.90
|
$185.50
|
$477.00
|
$1,192.50
|
$916.90
|
|
|
|
DNA
|
T
|
Std
|
|
| |
Phosphate
|
[PHO]
|
5', 3'
|
|
|
$24.38
|
$24.38
|
$30.74
|
$55.12
|
$62.43
|
$94.66
|
$223.13
|
|
|
|
Both
|
Both
|
Std
|
|
| |
Non-flourescent labels
|
|
Pricing
|
|
Additional Information
|
| |
Modification
|
Designator
|
Positions allowed
|
N/A
|
|
25 nmole
|
50 nmole
|
250 nmole
|
1 µmole
|
2 µmole
|
5 µmole
|
10 µmole
|
|
N/A
|
N/A
|
DNA or RNA
|
Tubes or Plates
|
Std or non-std
|
Notes
|
| |
Biotin
|
[BIO]
|
5', 3'
|
|
|
|
$56.18
|
$66.78
|
$128.26
|
$158.10
|
$232.62
|
$467.46
|
|
|
|
Both
|
Both
|
Std
|
|
| |
Biotin PC (Photocleavable)
|
[BioPC]
|
5'
|
|
|
|
$161.12
|
$161.12
|
$306.34
|
|
|
$1,526.40
|
|
|
|
DNA
|
T
|
Std
|
|
| |
Biotin-dT
|
[BIOdT]
|
5', Int
|
|
|
|
$212.00
|
$212.00
|
$339.20
|
$362.52
|
$692.32
|
$1,696.00
|
|
|
|
DNA
|
Both
|
Std
|
|
| |
Biotin-ON
|
[BioON]
|
5', Int
|
|
|
|
$61.48
|
$78.44
|
$128.26
|
$231.61
|
$579.03
|
$640.24
|
|
|
|
Both
|
T
|
Std
|
|
| |
Biotin-TEG STD (5' or 3')
|
[BIOTEG]
|
5', 3'
|
|
|
|
$97.52
|
$121.90
|
$159.00
|
$179.25
|
$317.21
|
$736.70
|
|
|
|
Both
|
Both
|
Std
|
|
| |
Biotin-TEG (internal)
|
[BIOTEGi]
|
Int
|
|
|
|
$56.18
|
$56.18
|
$111.30
|
$201.40
|
$503.50
|
$556.50
|
|
|
|
Both
|
Both
|
Std
|
|
| |
Digoxigenin (NHS Ester)
|
[DIG]
|
5', 3'
|
|
|
|
$143.10
|
$143.10
|
$212.00
|
|
|
$1,725.15
|
|
|
|
DNA
|
T
|
Std
|
|
| |
DNP (2,4-dinitrophenyl)
|
[DNP]
|
5', 3', Int
|
|
|
|
$215.00
|
$215.00
|
$235.00
|
|
|
$1,762.00
|
|
|
|
DNA
|
T
|
Std
|
|
| |
Modified Bases, Spacers, Miscellaneous
|
|
Pricing
|
|
Additional Information
|
| |
Modification
|
Designator
|
Positions allowed
|
N/A
|
|
25 nmole
|
50 nmole
|
250 nmole
|
1 µmole
|
2 µmole
|
5 µmole
|
10 µmole
|
|
N/A
|
N/A
|
DNA or RNA
|
Tubes or Plates
|
Std or non-std
|
Notes
|
| |
23ddC
|
[23ddC]
|
3'
|
|
|
|
$95.40
|
$95.40
|
$190.80
|
|
|
$975.20
|
|
|
|
DNA
|
T
|
Std
|
|
| |
5-Methyl dC
|
[5MedC]
|
5', 3', Int
|
|
|
|
$44.52
|
$55.65
|
$83.48
|
|
|
$625.93
|
|
|
|
DNA
|
T
|
Std
|
|
| |
Acrydite
|
[5Acrd]
|
5'
|
|
|
|
$89.04
|
$111.30
|
$167.48
|
$334.96
|
$503.50
|
$667.80
|
|
|
|
DNA
|
T
|
Std
|
|
| |
Cholesteryl-TEG
|
[CholTEG]
|
5', Int
|
|
|
|
$97.52
|
$97.52
|
$291.50
|
$583.00
|
$1,457.50
|
$1,484.00
|
|
|
|
Both
|
T
|
Std
|
|
| |
Cholesteryl
|
[Chol]
|
3'
|
|
|
|
$97.52
|
$97.52
|
$291.50
|
$583.00
|
$1,457.50
|
$1,484.00
|
|
|
|
DNA
|
T
|
Std
|
|
| |
5' Dabcyl-dT
|
[5DabsyldT]
|
5', Int
|
|
|
|
|
$164.30
|
$278.25
|
|
|
$0.00
|
|
|
|
DNA
|
T
|
Std
|
|
| |
deoxyInosine [I]
|
[I]
|
5', Int
|
|
|
$11.13
|
$11.13
|
$13.36
|
$24.38
|
$40.18
|
$53.37
|
$99.64
|
|
|
|
Both
|
Both
|
Std
|
|
| |
deoxyUridine [U]
|
[U]
|
5', Int
|
|
|
$11.13
|
$11.13
|
$13.36
|
$24.38
|
$39.27
|
$53.37
|
$99.64
|
|
|
|
Both
|
Both
|
Std
|
|
| |
dP + dK mixture
|
[dPdK]
|
5', Int
|
|
|
|
$205.64
|
$205.64
|
$328.60
|
|
|
$1,962.06
|
|
|
|
DNA
|
T
|
Std
|
|
| |
dT-5' (reversed base)
|
[dTrev]
|
3'
|
|
|
|
$59.55
|
$71.02
|
$108.99
|
$137.80
|
$238.50
|
$445.20
|
|
|
|
DNA
|
T
|
Std
|
|
| |
pdC
|
[pdC]
|
5', Int
|
|
|
$11.13
|
$11.13
|
$15.37
|
$24.38
|
|
|
$99.64
|
|
|
|
DNA
|
T
|
Std
|
|
| |
pdU
|
[pdU]
|
5', Int
|
|
|
$11.13
|
$11.13
|
$15.37
|
$24.38
|
|
|
$99.64
|
|
|
|
DNA
|
T
|
Std
|
|
| |
Phosphorothioation PTO Bond
|
*
|
Int
|
|
|
|
$3.71
|
$3.71
|
$5.30
|
$12.72
|
$25.44
|
$37.10
|
|
|
|
DNA
|
T
|
Std
|
|
| |
dSpacer
|
[Spd]
|
5', Int
|
|
|
|
$94.34
|
$111.30
|
$167.48
|
$206.44
|
$317.21
|
$667.80
|
|
|
|
DNA
|
T
|
Std
|
|
| |
Spacer C18
|
[SP18]
|
5', Int
|
|
|
|
$50.88
|
$61.48
|
$99.64
|
$123.86
|
$190.32
|
$400.68
|
|
|
|
DNA
|
T
|
Std
|
|
| |
Spacer C3
|
[SpC3]
|
5', Int
|
|
|
|
$55.12
|
$66.78
|
$103.88
|
$116.81
|
$159.11
|
$365.70
|
|
|
|
DNA
|
Both
|
Std
|
|
| |
Spacer C9
|
[SpC9]
|
5', Int
|
|
|
|
$68.90
|
$73.14
|
$103.88
|
|
|
$365.70
|
|
|
|
DNA
|
T
|
Std
|
|
| |
TINA
|
[TINA]
|
5'
|
|
|
|
$55.12
|
$67.84
|
$116.60
|
$233.20
|
$477.00
|
$0.00
|
|
|
|
DNA
|
T
|
Std
|
|
| |
2'-Fluoro-A
|
[2FlA]
|
5', 3', Int
|
|
|
$23.32
|
$43.73
|
$43.73
|
$66.46
|
|
|
$338.14
|
|
|
|
RNA
|
T
|
Std
|
|
| |
2'-Fluoro-C
|
[2FlC]
|
5', 3', Int
|
|
|
$23.32
|
$43.73
|
$43.73
|
$66.46
|
|
|
$338.14
|
|
|
|
RNA
|
T
|
Std
|
|
| |
2'-Fluoro-G
|
[2FlG]
|
5', 3', Int
|
|
|
$23.32
|
$43.73
|
$43.73
|
$66.46
|
|
|
$338.14
|
|
|
|
RNA
|
T
|
Std
|
|
| |
2'-Fluoro-U
|
[2FlU]
|
5', 3', Int
|
|
|
$23.32
|
$43.73
|
$43.73
|
$66.46
|
|
|
$338.14
|
|
|
|
RNA
|
T
|
Std
|
|
| |
2'-O-Methyl A
|
[2OMeA]
|
5', 3', Int
|
|
|
|
$10.02
|
$14.47
|
$22.26
|
$44.52
|
$82.68
|
$172.78
|
|
|
|
RNA
|
T
|
Std
|
|
| |
2'-O-Methyl C
|
[2OMeC]
|
5', 3', Int
|
|
|
|
$10.02
|
$14.47
|
$22.26
|
$44.52
|
$82.68
|
$172.78
|
|
|
|
RNA
|
T
|
Std
|
|
| |
2'-O-Methyl G
|
[2OMeG]
|
5', 3', Int
|
|
|
|
$10.02
|
$14.47
|
$22.26
|
$44.52
|
$82.68
|
$172.78
|
|
|
|
RNA
|
T
|
Std
|
|
| |
2'-O-Methyl U
|
[2OMeU]
|
5', 3', Int
|
|
|
|
$10.02
|
$14.47
|
$22.26
|
$44.52
|
$82.68
|
$172.78
|
|
|
|
RNA
|
T
|
Std
|
|
| |
2-MethoxyEthoxy A (MOE)
|
[2MoeA]
|
5', 3', Int
|
|
|
|
$21.20
|
$27.56
|
$48.76
|
$61.48
|
|
|
|
|
|
RNA
|
T
|
Std
|
|
| |
2-MethoxyEthoxy MeC (MOE)
|
[2MoeC]
|
5', 3', Int
|
|
|
|
$21.20
|
$27.56
|
$48.76
|
$61.48
|
|
|
|
|
|
RNA
|
T
|
Std
|
|
| |
2-MethoxyEthoxy G (MOE)
|
[2MoeG]
|
5', 3', Int
|
|
|
|
$21.20
|
$27.56
|
$48.76
|
$61.48
|
|
|
|
|
|
RNA
|
T
|
Std
|
|
| |
2-MethoxyEthoxy T (MOE)
|
[2MoeU]
|
5', 3', Int
|
|
|
|
$21.20
|
$27.56
|
$48.76
|
$61.48
|
|
|
|
|
|
RNA
|
T
|
Std
|
|
| |
Click Chemistry
|
|
Pricing
|
|
Additional Information
|
| |
Modification
|
Designator
|
Positions allowed
|
N/A
|
|
25 nmole
|
50 nmole
|
250 nmole
|
1 µmole
|
2 µmole
|
5 µmole
|
10 µmole
|
|
N/A
|
N/A
|
DNA or RNA
|
Tubes or Plates
|
Std or non-std
|
Notes
|
| |
Azide (NHS Ester)
|
[Azide]
|
5', 3'
|
|
|
|
$116.60
|
$148.40
|
$212.00
|
|
|
$1,484.00
|
|
|
|
DNA
|
T
|
Std
|
|
| |
Hexynyl
|
[Hexynyl]
|
5', 3', Int
|
|
|
|
$125.08
|
$155.82
|
$237.44
|
|
|
$943.40
|
|
|
|
DNA
|
T
|
Std
|
|
| |
Mixed/Degenerate Bases (Wobbles)
|
|
Pricing
|
|
Additional Information
|
| |
Modification
|
Designator
|
Positions allowed
|
N/A
|
|
25 nmole
|
50 nmole
|
250 nmole
|
1 µmole
|
2 µmole
|
5 µmole
|
10 µmole
|
|
N/A
|
N/A
|
DNA or RNA
|
Tubes or Plates
|
Std or non-std
|
Notes
|
| |
Machine-Mixed Wobble
|
See below
|
5', 3', Int
|
|
|
Standard base price
|
Standard base price
|
Standard base price
|
Standard base price
|
Standard base price
|
Standard base price
|
Standard base price
|
|
|
|
Both
|
Both
|
Std
|
|
| |
Hand-Mixed Wobble
|
[%-%-%-%]
|
5', 3', Int
|
|
|
$8.48
|
$8.48
|
$8.48
|
$10.60
|
$21.20
|
$53.00
|
$100.70
|
|
|
|
Both
|
Both
|
Std
|
User defined
|
| |
List of Wobble Bases
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Both
|
Both
|
Std
|
|
| |
N (A+C+G+T)
|
N
|
5', 3', Int
|
|
|
|
|
|
|
|
|
|
|
|
|
Both
|
Both
|
Std
|
N = (A, 25%; C, 25%; G, 25%; T, 25%)
|
| |
B (C+G+T)
|
B
|
5', 3', Int
|
|
|
|
|
|
|
|
|
|
|
|
|
Both
|
Both
|
Std
|
B = (C, 33.3%; G, 33.3%; T, 33.3%)
|
| |
D (A+G+T)
|
D
|
5', 3', Int
|
|
|
|
|
|
|
|
|
|
|
|
|
Both
|
Both
|
Std
|
D = (A-33.3%, G-33.3%, T-33.3%)
|
| |
H (A+C+T)
|
H
|
5', 3', Int
|
|
|
|
|
|
|
|
|
|
|
|
|
Both
|
Both
|
Std
|
H = (A, 33.3%; C, 33.3%; T, 33.3%)
|
| |
V (A+C+G)
|
V
|
5', 3', Int
|
|
|
|
|
|
|
|
|
|
|
|
|
Both
|
Both
|
Std
|
V = (A, 33.3%; C, 33.3%; G, 33.3%)
|
| |
K (G+T)
|
K
|
5', 3', Int
|
|
|
|
|
|
|
|
|
|
|
|
|
Both
|
Both
|
Std
|
K = (G, 50%; T, 50%)
|
| |
M (A+C)
|
M
|
5', 3', Int
|
|
|
|
|
|
|
|
|
|
|
|
|
Both
|
Both
|
Std
|
M = (A, 50%; C, 50%)
|
| |
R (A+G)(purines)
|
R
|
5', 3', Int
|
|
|
|
|
|
|
|
|
|
|
|
|
Both
|
Both
|
Std
|
R = (A, 50%; G, 50%)
|
| |
S (C+G)(strong bonds)
|
S
|
5', 3', Int
|
|
|
|
|
|
|
|
|
|
|
|
|
Both
|
Both
|
Std
|
S = (C, 50%; G, 50%)
|
| |
W (A+T)(weak bonds)
|
W
|
5', 3', Int
|
|
|
|
|
|
|
|
|
|
|
|
|
Both
|
Both
|
Std
|
W = (A, 50%; T, 50%)
|
| |
Y (C+T)(pyrimidines)
|
Y
|
5', 3', Int
|
|
|
|
|
|
|
|
|
|
|
|
|
Both
|
Both
|
Std
|
Y = (C, 50%; T, 50%)
|
*Ester mods are attached through a dT base. Incorporation of the internal version will add a dT nucleotide at that position. To avoid adding an extra nucleotide, replace an existing T nucleotide in your sequence with the required modification.