All Oligonucleotides Nanopore Sequencing Sanger Sequencing Gene Synthesis

Oligonucleotides

DNA Bases

Synthesis Scale	Tube Price	Plate Price	Min. Yield	Max Length
EXTREmer 4 nmole	$0.95	$0.50	4 nmole	200 mer
EXTREmer 25 nmole	$1.95	$1.05	25 nmole	200 mer
4 nmole	-	$0.09	1.5 nmole	60 mer
10 nmole	$0.30	$0.13	4 nmole	70 mer
25 nmole	$0.42	$0.22	10 nmole	80 mer
50 nmole	$0.81	$0.36	20 nmole	90 mer
250 nmole	$1.43	$0.61	50 nmole	125 mer
1 umole	$3.05	$1.25	200 nmole	125 mer
2 umole	$4.75	-	400 nmole	125 mer
5 umole	$11.40	-	1000 nmole	125 mer
10 umole	$19.95	-	2000 nmole	125 mer

*Unmodified, unpurified EXTREmer oligos will have a minimum yield of 4 or 25 nmol. Purified and/or modified EXTREmer oligos have a lower minimum yield, typically 1 nmole

RNA Bases

Scale	Price
50 nmole	$5.25
250 nmole	$8.40
1 µmole	$10.50
10 µmole	$89.25

LNA Bases

Scale	Price
50 nmole	$21.00
250 nmole	$27.83
1 µmole	$46.20

Express Products

Product	Price
ExpressOligos (Tubes)	No additional charge
ExpressPlates	$45.00/plate

Formulation

Custom normalization in water, TE, or TRIS: $6.36 per tube for all scales up to 1 umole, 2 umole is $15.00, 5 umole is $30.74, and 10 umole is $92.22.
LabSet (normalization in 100µM in TE, pH 8.0): $3.65 per tube

Aliquots / Stamping

Part #	Tubes versus Plates	Price
1235-0000A	Tube Aliquot	$5.00
1235-0000AP	Plate aliquot / stamp	$24.00

General Notes

*Minimum Yield based on oligos in tubes from 20–45 bases, inclusive.

Note: PAGE purification is available for oligos greater than 20 bases in length. 2-Step purification is required for HPLC-purified oligos greater than 60 bases in length, and for PAGE-purified oligos greater than 69 bases in length.

Plate-format oligos are available in the 10 nmole, 100 nmole, and 0.2 μmole scales. These oligos are delivered in 96-well plates and concentration normalized or lyophilized. Place orders for up to 1000 plate-format oligos online or email your order for more than 1000 oligos using our convenient upload forms.

qPCR Probes

Combination	Synthesis Scale
Combination	50 nmole	250 nmole	1 µmole
5' 6-FAM + 3' BBQ650	$214.00	$304.00	$456.00
5' 6-FAM + 3' BHQ 1	$214.00	$304.00	$456.00
5' HEX + 3' BHQ 1	$290.00	$418.00	$570.00
5' JOE + 3' BHQ 1	Not available	$414.00	$565.00
5' Oregon Green + 3' BHQ 1	Not available	$414.00	$565.00
5' TET + 3' BHQ 1	$290.00	$418.00	$570.00
5' CAL Fluor Red 610 + BHQ2	$416.00	$940.00	$1056.00
5' Cyanine3 + 3' BHQ 2	$290.00	$418.00	$570.00
5' Cyanine3.5 + 3' BHQ 2	Not available	$414.00	$565.00
5' Cyanine5 + 3' BHQ 2	$290.00	$418.00	$570.00
5' Cyanine5.5 + 3' BHQ 2	Not available	$414.00	$565.00
5' HEX 3' + 3' BHQ 2	$290.00	$418.00	$570.00
5' ROX 3' + 3' BHQ 2	Not available	$414.00	$565.00
5' TAMRA + 3' BHQ 2	Not available	$414.00	$565.00
5' Texas Red + 3' BHQ 2	Not available	$414.00	$565.00
5' TF1 + 3' TQ1	Not available	$414.00	$565.00
5' TF2 + 3' TQ2	Not available	$414.00	$565.00
5' TF3 + 3' TQ3	Not available	$414.00	$565.00
5' TF5 + 3' TQ5	Not available	$414.00	$565.00
5' 6-FAM + 3' Tamra	$214.00	$304.00	$456.00
5' HEX + 3' Tamra	$290.00	$418.00	$570.00
5' TET + 3' Tamra	$214.00	$304.00	$456.00

MGB Probes

	5 nmole	20 nmole	40 nmole
MGB Probe (FAM)	$240.00	$423.00	$692.00
MGB Probe (HEX)	$279.00	$532.00	$788.00
MGB Probe (YAKYE)	$279.00	$532.00	$788.00
MGB Probe (Cy5)	$279.00	$532.00	$788.00

Purification Pricing

Syntheis Scale	50 nmole	250 nmole	1 µmole	2 µmole	5 µmole	10 µmole
HPSF Cartridge Method	$18.72	$23.35	$32.00	$62.20	$155.51	$311.00
Min. Yield*	14 nmole	35 nmole	140 nmole	280 nmole	700 nmole	1400 nmole
HPLC	$50.00	$85.00	$130.00	$211.40	$291.50	$465.00
Min. Yield*	3.75 nmole	12.5 nmole	50 nmole	100 nmole	250 nmole	500 nmole
PAGE	$74.00	$105.00	$160.00	$245.00	$870.00	$1300.00
Min. Yield*	2 nmole	6.5 nmole	25 nmole	50 nmole	125 nmole	250 nmole
Duel HPLC	$88.20	$157.50	$210.00	$307.40	$615.00	$798.00
Min. Yield*	2 nmole	6.5 nmole	25 nmole	50 nmole	125 nmole	250 nmole
PAGE / HPLC 2-Step	$84.00	$162.00	$298.00	$560.00	$1160.00	$1750.00
Min. Yield*	0.5 nmole	3 nmole	12.5 nmole	25 nmole	62.5 nmole	125 nmole

Notes:

Min yield is determined for standard oligos. The delivered quantity is dependent on the sequence composition, length, and modifications.
2-Step purification is required for HPLC-purified oligos greater than 60 bases in length, and for PAGE-purified oligos greater than 69 bases in length.
PAGE purification is available for oligos greater than 20 bases in length.

NGS Grade

Custom Oligos			EXTREmer Oligos
Synthesis Scale	Tubes	Plates	Synthesis Scale	Tubes	Plates
4 nmole	--	$2.63	4 nmole	$10.50	$4.73
10 nmole	$7.35	$2.63	25 nmole	$15.75	$7.35
25 nmole	$7.35	$2.63
50 nmole	$10.50	$4.73
250 nmole	$10.50	$4.73
1 µmole	$15.75	$7.35
2 µmole	$18.90
5 µmole	$15.15
10 µmole	$57.75

Standard Modifications

Eurofins Genomics offers a wide variety of modifications for both DNA and RNA oligos to meet the needs of virtually any project. Modifications that are regularly stocked in-house are considered the "standard modifications portfolio." Standard modifications are listed below.

Non-standard modifications

Non-standard modifications refer to a.) custom modifications supplied by the customer, b.) special requests from customers for modifications not listed in the standard portfolio, and c.) modifications that we have prior expertise with but may not keep in stock due to the infrequency of orders. In short, any modification that is not listed in the standard portfolio. Eurofins Genomics can accommodate requests for non-standard modifications. We understand that much of science revolves around experimentation and new needs arise from new techniques.

Do not see a modification you want? Contact us to request a modification. We may be able to accommodate non-standard modifications.

	Specifications									Pricing
Fluorophores	Designator	5'	Int	3'	DNA or RNA	Tubes or Plates	Max Abs (nm)	Max Em (nm)	Extinction coefficient (M-1cm–1)	25 nmole	50 nmole	250 nmole	1 µmole	2 µmole	5 µmole	10 µmole	Notes
Alexa Fluor 350	[Alexa350]	✓	✓	✓	DNA	T	346	424	19000	--	$653.00	$653.00	$1,686.00	$2,774.00	$6,935.00	--	Alternative to AMCA
CF 405S succinimidyl ester (CF405SN)	[CF405SN]	✓	✓	✓	DNA	T	404	431	33000	--	--	$263.00	$1180.00	--	--	--	--
Tide Fluor 1	[TF1]	✓	✓	✓	DNA	T	341	447		--	$140.00	$140.00	$248.00	$320.00	$800.00	$1,372.00
ATTO 390	[ATTO390]	✓	✓	✓	DNA	T	390	479	24000	--	$152.00	$221.00	$305.00	$551.00	$1,448.75	--
5-FAM	[5FAM]	✓			Both	T	492	518		--	$55.00	$70.00	$145.00	$158.00	$230.00	$525.00	Alternative to CY2, DY-495, ATTO 495
Alexa Fluor 488	[Alexa488]	✓	✓	✓	DNA	T	496	519	71000	--	$300.00	$300.00	$450.00	$509.00	$778.05	--
Fluorescein	[FL]	✓	✓		DNA	T	495	520	83000	--	$65.00	$81.00	$175.00	$248.00	$452.00	--	Alternative to DY-495, ATTO 495
6-FAM	[FAM]	✓		✓	Both	Both	495	521	75000	--	$68.00	$85.00	$184.00	$239.00	$342.00	$525.00
Fluorescein dT	[FLUdT]	✓	✓		DNA	T	494	522	75000	--	$200.00	$225.00	$320.00	$359.10	$685.90	$1,600.00	Alternative to DY-495, ATTO 495
Tide Fluor 2	[TF2]	✓	✓	✓	DNA	T	499	522		--	$140.00	$140.00	$248.00	$320.00	$800.00	$929.00
ATTO 488	[ATTO488]	✓	✓	✓	DNA	T	501	523	90000	--	$205.00	$273.00	$378.00	$467.40	$718.20	--	Alternative to Cy2
Oregon Green 488	[OG488]	✓	✓	✓	DNA	T	496	524	76000	--	$375.00	$375.00	$565.00	$638.40	$978.50	$5,750.00	Alternative to Cy2
TET	[TET]	✓			Both	Both	519	539	86000	--	$75.00	$94.00	$190.00	$380.00	$950.00	$750.00	Alternative to CAL Fluor Gold 540
CAL Fluor Gold 540	[CalFluor540]	✓			DNA	T			522		--	--	--	--	--	--	Alternative to 81100
JOE	[JOE]	✓	✓	✓	DNA	T	520	548	73000	--	$205.00	$205.00	$310.00			$7,400.00	Alternative to CAL Fluor Gold 540, Rhodamine 6G
Yakima Yellow	[YAKYE]	✓			DNA	T	530	549		--	$79.00	$100.00	$201.40	$265.00	$530.00	$1,060.00	Alternative to VIC, CAL Fluor 560
Alexa Fluor 532	[Alexa532]	✓	✓	✓	DNA	T	532	553	81000	--	$375.00	$375.00	$565.00	$638.40	$978.50	$5,750.00
ATTO 532	[ATTO532]	✓	✓	✓	DNA	T	532	553	115000	--	$205.00	$273.00	$378.00	$469.30	$718.20	--
HEX	[HEX]	✓			Both	Both	537	556	96000	--	$75.00	$94.00	$190.00	$214.70	$324.90	$683.00	Alternative to VIC, CAL Fluor 560, SIMA
Alexa Fluor 555	[Alexa555]	✓	✓	✓	DNA	T	555	565	150000	--	$653.00	$653.00	$1,686.00	$2,774.00	$6,935.00	--	Alternative to Cy3, TRITC & TMR, Alexa Fluor 546
Alexa Fluor 546	[Alexa546]	✓	✓	✓	DNA	T	556	573	104000	--	$375.00	$375.00	$565.00	$633.65	$978.50	$5,750.00
ATTO 550	[ATTO550]	✓	✓	✓	DNA	T	554	576	120000	--	$205.00	$273.00	$378.00	$467.40	$718.20	--	Alternative to NED, Cy3, Rhodamine B & 6G
TAMRA dT	[TAMdT]	✓	✓		DNA	T	544	576	90000	--	$156.00	$283.00	$422.00	$693.50	$1,733.75	--
Tide Fluor 3	[TF3]	✓	✓	✓	DNA	T	554	578		--	$140.00	$140.00	$248.00	$320.00	$800.00	$929.00
TAMRA	[TAM]			✓	DNA	Both	556	580	89000	--	$98.00	$115.00	$175.00	$194.75	$299.25	$780.00	Alternative to Rhodamine 6G, Rhodamine B, CAL Fluor 590
5-Tamra (ester)	[TMR5]	✓			DNA	T	557	583		--	$130.00	$155.00	$250.00	$279.30	$738.15	$1,700.00
CAL Fluor 590	[CalFluor590]	✓			DNA	T	569	591	79000	--	350.00	$350.00	$455.00	$865.50	$2,161.25	$3,640.00
ATTO 565	[ATTO565]	✓	✓	✓	DNA	T	563	592	120000	--	$174.00	$263.00	$352.00	$435.10	$668.80	--	Alternative to PET, Alexa Fluor 594
ROX	[ROX]	✓	✓	✓	DNA	T	575	602	82000	--	$174.00	$174.00	$263.00	$324.90	$498.75	$1,790.00	Alternative to Texas Red, Alexa Fluor 594, CAL Fluor Red 610
Alexa Fluor 568	[Alexa568]	✓	✓	✓	DNA	T	578	603	91000	--	$653.00	$653.00	$1,686.00	$2,774.00	$6,935.00	--
Texas Red	[TxRed]	✓	✓	✓	DNA	T	583	603	116000	--	$200.00	$242.00	$347.00	$428.25	$658.35	--	Alternative to ROX, Alexa Fluor 594
Cyanine3.5 dye	[Cy35]	✓	✓		DNA	T	591	604	116000	--	$173.00	$185.00	$294.00	$532.50	$1,330.00	--	Alternative to Alexa Fluor 594, CAL Fluor Red 610
CAL Fluor Red 610	[CalFluor610]	✓			DNA	T	590	610	108000	--	$350.00	$350.00	$455.00	$865.50	$2,161.25	$3,640.00	Alternative to Texas Red, ROX, Alexa Fluor® 594
Tide Fluor 4	[TF4]	✓	✓	✓	DNA	T	588	610		--	$140.00	$140.00	$248.00	$320.00	$800.00	$929.00
Alexa Fluor 594	[Alexa594]	✓	✓	✓	DNA	T	590	617	73000	--	$440.00	$440.00	$670.00	$753.35	$2,498.00	$6,450.00	Alternative to ATTO 594, CAL Fluor Red 610
ATTO 590	[ATTO590]	✓	✓	✓	DNA	T	594	624	120000	--	$174.00	$263.00	$352.00	$434.15	$668.80	--
Alexa Fluor 633	[Alexa633]	✓	✓	✓	DNA	T	632	647	239000	--	$653.00	$653.00	$1,686.00	$2,774.00	$6,935.00	--
ATTO 633	[ATTO633]	✓	✓	✓	DNA	T	629	657	130000	--	$205.00	$273.00	$378.00	$467.40	$718.20	--	Alternative to LIZ, Alexa Fluor 633
Cyanine5 dye	[Cy5]	✓			Both	T	646	662	250000	--	$107.00	$135.00	$210.00	$233.70	$489.25	$1,300.00	Alternative to Quasar 670, TYE 655, TYE 665
Alexa Fluor 647	[Alexa647]	✓	✓	✓	DNA	T	650	665	239000	--	$300.00	$300.00	$450.00	$504.45	$778.05	--	Alternative to Cy5, Quasar 670
ATTO 647N	[ATTO647N]	✓	✓	✓	DNA	T	644	669	150000	--	$205.00	$273.00	$378.00	$467.40	$718.20	--	Alternative to Cy5, Quasar 670
Tide Fluor 5	[TF5]	✓	✓	✓	DNA	T	656	670		--	$140.00	$140.00	$248.00	$320.00	$800.00	$929.00
ATTO 655	[ATTO655]	✓	✓	✓	DNA	T	663	684	125000	--	$152.00	$221.00	$305.00	$579.50	$1,448.75	--
Alexa Fluor 660	[Alexa660]	✓	✓	✓	DNA	T	663	690	132000	--	$440.00	$440.00	$670.00	$753.35	$1,154.25	$6,450.00
Alexa Fluor 680	[Alexa680]	✓	✓	✓	DNA	T	679	702	184000	--	$653.00	$653.00	$1,686.00	$2,774.00	$6,935.00	--	Alternative to Alexa Fluor 680, Alexa Fluor 700
Tide Fluor 6	[TF6]	✓	✓	✓	DNA	T	686	702		--	$140.00	$140.00	$248.00	$320.00	$800.00	$929.00
Cyanine5.5 dye	[Cy55]	✓			DNA	T	688	707	209000	--	$184.00	$205.00	$310.00	$294.50	$589.00	$3,100.00	Alternative to Alexa Fluor 680, TYE 705
ATTO 700	[ATTO700]	✓	✓	✓	DNA	T	700	719	120000	--	$152.00	$221.00	$305.00	$579.50	$1448.75	--
Alexa Fluor 700	[Alexa700]	✓	✓	✓	DNA	T	702	723	192000	--	$653.00	$653.00	$1,686.00	$2,774.00	$6,935.00	--	Alternative to IRDye 700, Quasar 705
ATTO 740	[ATTO740]	✓	✓	✓	DNA	T	740	764	120000	--	$145.00	$210.00	$290.00	--	--	--	Alternative to Cy7, Alexa Fluor 740
Alexa Fluor 750	[Alexa750]	✓	✓	✓	DNA	T	749	775	240000	--	$440.00	$440.00	$670.00	$753.35	$1154.25	--
Tide Fluor 7	[TF7]	✓	✓	✓	DNA	T	756	775		--	$140.00	$140.00	$248.00	$320.00	$800.00	$929.00
Tide Fluor 8	[TF8]	✓	✓	✓	DNA	T	787	808		--	$140.00	$140.00	$248.00	$320.00	$800.00	$929.00
Quenchers
BBQ650	[BBQ650]	✓		✓	DNA	T	650	n/a	33000		$257.25	$257.25	$294.00	$588.00	$1470.00
BHQ1	[BHQ1]	✓		✓	DNA	T	534	n/a	34000	--	$110.00	$145.00	$210.00	$359.10	$1005.00	$2000.00
BHQ1 dT	[BHQ1dT]	✓	✓		DNA	T	534	n/a	34000	--	--	$163.00	$252.00	$480.00	$1,200.00	--
BHQ2	[BHQ2]	✓		✓	DNA	T	579	n/a	91000	--	$110.00	$145.00	$210.00	$270.75	$359.10	$2000.00
BHQ2 dT	[BHQ2dT]	✓	✓		DNA	T	579	n/a	91000	--	--	$278.00	$383.00	$693.50	$1,733.75	--
Dabcyl STANDARD	[DAB}			✓	DNA	T	453	n/a	32000		$92.00	$115.00	$175.00	$194.75	$374.30	$865.00
Dabcyl dT	[DABdT]	✓	✓		DNA	T	478	n/a	32000	--	$285.00	$382.50	$382.50	$690.00	$1,725.00	--
TAMRA	[TAM]	✓		✓	DNA	T	557	n/a	91000	--	$98.00	$115.00	$175.00	$194.75	$299.25	$780.00
Tide Quencher 1	[TQ1]			✓	DNA	T	490	n/a	20000	--	$46.00	$58.00	$116.00	$200.00	$375.00	$635.00
Tide Quencher 2	[TQ2]			✓	DNA	T	515	n/a	21000	--	$46.00	$58.00	$116.00	$200.00	$375.00	$635.00
Tide Quencher 3	[TQ3]			✓	DNA	T	570	n/a	22000	--	$46.00	$58.00	$116.00	$200.00	$375.00	$635.00
Tide Quencher 5	[TQ5]			✓	DNA	T	670	n/a	24000	--	$46.00	$58.00	$116.00	$200.00	$375.00	$635.00
Mixed/Degenerate Bases (Wobbles)
N (A+C+G+T) Wobble	N	✓	✓	✓	Both	Both	-	-	-	$0.38	$0.50	$1.26	$2.57			$17.00	N = (A, 25%; C, 25%; G, 25%; T, 25%)
B (C+G+T) Wobble	B	✓	✓	✓	Both	Both	-	-	-	$0.38	$0.50	$1.27	$2.58			$17.01	B = (C, 33.3%; G, 33.3%; T, 33.3%)
D (A+G+T) Wobble	D	✓	✓	✓	Both	Both	-	-	-	$0.38	$0.50	$1.28	$2.59			$17.02	D = (A-33.3%, G-33.3%, T-33.3%)
H (A+C+T) Wobble	H	✓	✓	✓	Both	Both	-	-	-	$0.38	$0.50	$1.29	$2.60			$17.03	H = (A, 33.3%; C, 33.3%; T, 33.3%)
V (A+C+G) Wobble	V	✓	✓	✓	Both	Both	-	-	-	$0.38	$0.50	$1.30	$2.61			$17.04	V = (A, 33.3%; C, 33.3%; G, 33.3%)
K (G+T) Wobble	K	✓	✓	✓	Both	Both	-	-	-	$0.38	$0.50	$1.31	$2.62			$17.05	K = (G, 50%; T, 50%)
M (A+C) Wobble	M	✓	✓	✓	Both	Both	-	-	-	$0.38	$0.50	$1.32	$2.63			$17.06	M = (A, 50%; C, 50%)
R (A+G)(purines) Wobble	R	✓	✓	✓	Both	Both	-	-	-	$0.38	$0.50	$1.33	$2.64			$17.07	R = (A, 50%; G, 50%)
S (C+G)(strong bonds) Wobble	S	✓	✓	✓	Both	Both	-	-	-	$0.38	$0.50	$1.34	$2.65			$17.08	S = (C, 50%; G, 50%)
W (A+T)(weak bonds) Wobble	W	✓	✓	✓	Both	Both	-	-	-	$0.38	$0.50	$1.35	$2.66			$17.09	W = (A, 50%; T, 50%)
Y (C+T)(pyrimidines) Wobble	Y	✓	✓	✓	Both	Both	-	-	-	$0.38	$0.50	$1.36	$2.67			$17.10	Y = (C, 50%; T, 50%)
Wobble, Hand-Mixed	[%-%-%-%]	✓	✓

Pricing

Oligonucleotides

DNA / RNA Bases

Probes

Purification

Purification Pricing

Modifications