The world of genotyping - benefit from the whole package

DNA Extraction

At the beginning of all analyses DNA needs to be extracted. Here we count, especially with sensitive samples, on our long-lasting experience in forensic DNA trace analysis or clincal trial samples. Single analysis of samples or parallel preparation of ten thousands of blood and tissue samples, our DNA know how sets standards. Our well-trained laboratory staffs work according to a certified quality management system. Automated platforms and pipetting robots facilitate the high-throughput analysis and enable a consistent quality standard.

SNP Genotyping

High-throughput genotyping of one to hundred SNPs per sample for following applications:

• Population genetics
• Biomarker determination and validation
• Association studies (also with pooled DNA and mutations with low frequencies)
• Parentage and pedigree testing
• Traceability
• Genomic selection
• Fine mapping of gene loci, haplotyping

Genotyping of microsatellites / STR / SSR / FLA

Genotyping of microsatellites by fragment length analysis (FLA) of fluorescent PCR products with Capillary Electrophoresis. Expect fast and accurate services with more than 40 thermal cyclers and electrophoretic separation on ABI 3130 and ABI 3100 automatic sequencers.
Typical applications:

• DNA forensics
• parentage testing and genealogy of human
• parentage and pedigree testing of animals
• population genetics
• QTL studies

Sequencing based genotyping

Discover, validate and genotype: from single markers to whole genome

Marker discovery, validation and genotyping can be very efficient with next generation sequencing methods. In many cases, Sanger sequencing is still the best method, especially for more complex or selected DNA markers.

Copy number variation

Analysis of copy number variations via

• Long-range PCR
• Quantitative PCR
• Microarrays
• Next generation sequencing

Genome wide association studies

Genome-wide association study (GWAS), are an examination of many common genetic variants in different individuals to see if any variant is associated with a trait. Genome wide association studies typically focus on associations between single-nucleotide polymorphisms (SNPs) and traits like major diseases. For genome wide association studies, we offer the whole range of Affymetrix GeneChips and Illumina BeadChips, incl. GoldenGate and Infinium assays

Analysis of target genes

We analyse target genes to search for genetic variants applying different methods on behalf of the customer.

Human identification

We are a leading provider of forensic DNA profiling services to police forces and legal services organisations. Our human identification services include cell line identification, human contamination tracing and human clinical sample identification in research, biotechnological and pharmaceutical applications.

Cell line authentication

Eurofins provides full cell line identification services from DNA extraction to official certificates of authenticity that are accepted by peer-reviewed scientific journals.

Strict confidentiality is ensured for every project. The high quality of our service is overseen by a professional quality management team. We are certified according to DIN EN ISO 9001:2008 and 17025:2005 (D-PL-13372-01-00).

Make time your best friend - we will find the perfect solution for you.