Standard Oligonucleotide Modifications for custom DNA and RNA synthesis

Eurofins Genomics offers a wide variety of modifications for both DNA and RNA oligos to meet the needs of virtually any project. Modifications that are regularly stocked in-house are considered the "standard modifications portfolio." Standard modifications are listed below.

Non-standard modifications

Non-standard modifications refer to any modification that is not listed in the standard portfolio. Typically, non-standard modifications derive from a.) custom modifications supplied by the customer, b.) special requests from customers for modifications not listed in the standard portfolio, and c.) modifications that we have prior expertise with but may not keep in stock due to the infrequency of orders. Eurofins Genomics can accommodate requests for non-standard modifications. We understand that much of science revolves around experimentation and new needs arise from new techniques.  Do not see a modification you want? Contact us to request a modification.

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Fluorophores

 

Pricing

 

Additional Information

 

Modification

Designator

Positions allowed

Max Em (nm)

 

25 nmole price

50 nmole price

250 nmole price

1 mole price

2 mole price

5 mole price

10 mole price

 

Extinction coefficient (M-1cm 1)

Max Abs (nm)

DNA or RNA

Tubes or Plates

Std or
non-std

Notes

 

Alexa Fluor 350

[Alexa350]

5', 3', Int

424

 

 

$692.18

$692.18

$1,787.16

$2,940.44

$7,351.10

 

 

19000

346

DNA

T

Std

 

 

CF 405S succinimidyl ester (CF405SN)

[CF405SN]

5', 3', Int

431

 

 

 

$278.78

$1,250.80

 

 

 

 

33000

404

DNA

T

Std

 

 

Tide Fluor 1

[TF1]

5', 3', Int

447

 

 

$148.40

$148.40

$262.88

$339.20

$848.00

$1,454.32

 

 

341

DNA

T

Std

 

 

ATTO 390

[ATTO390]

5', 3', Int

479

 

 

$161.12

$234.26

$323.30

$584.06

$1,535.68

 

 

24000

390

DNA

T

Std

 

 

5-FAM

[5FAM]

5'

518

 

 

$58.30

$74.20

$153.70

$167.48

$243.80

$556.50

 

 

492

Both

T

Std

 

 

Alexa Fluor 488

[Alexa488]

5', 3', Int

519

 

 

$318.00

$318.00

$477.00

$539.54

$824.73

 

 

71000

496

DNA

T

Std

 

 

Fluorescein

[FL]

5', Int

520

 

 

$68.90

$85.86

$185.50

$262.88

$479.12

 

 

83000

495

DNA

T

Std

 

 

6-FAM

[FAM]

5', 3'

521

 

 

$72.08

$90.10

$195.04

$253.34

$362.52

$556.50

 

75000

495

Both

Both

Std

 

 

Fluorescein dT

[FLUdT]

5', Int

522

 

 

$212.00

$238.50

$339.20

$380.65

$727.05

$1,696.00

 

75000

494

DNA

T

Std

 

 

Tide Fluor 2

[TF2]

5', 3', Int

522

 

 

$148.40

$148.40

$262.88

$339.20

$848.00

$984.74

 

 

499

DNA

T

Std

 

 

ATTO 488

[ATTO488]

5', 3', Int

523

 

 

$217.30

$289.38

$400.68

$495.44

$761.29

 

 

90000

501

DNA

T

Std

 

 

Oregon Green 488

[OG488]

5', 3', Int

524

 

 

$397.50

$397.50

$598.90

$676.70

$1,037.21

$6,095.00

 

76000

496

DNA

T

Std

 

 

TET

[TET]

5'

539

 

 

$79.50

$99.64

$201.40

$402.80

$1,007.00

$795.00

 

86000

519

Both

Both

Std

 

 

CAL Fluor Gold 540

[CalFluor540]

5'

543

 

 

$397.50

$397.50

$598.90

$676.70

$1,037.21

$6,095.00

 

81100

522

DNA

T

Std

 

 

JOE

[JOE]

5', 3', Int

548

 

 

$217.30

$217.30

$328.60

$0.00

$0.00

$7,844.00

 

73000

520

DNA

T

Std

 

 

Yakima Yellow

[YAKYE]

5'

549

 

 

$83.74

$106.00

$213.48

$280.90

$561.80

$1,123.60

 

 

530

DNA

T

Std

 

 

Alexa Fluor 532

[Alexa532]

5', 3', Int

553

 

 

$397.50

$397.50

$598.90

$676.70

$1,037.21

$6,095.00

 

81000

532

DNA

T

Std

 

 

ATTO 532

[ATTO532]

5', 3', Int

553

 

 

$217.30

$289.38

$400.68

$497.46

$761.29

 

 

115000

532

DNA

T

Std

 

 

HEX

[HEX]

5'

556

 

 

$79.50

$99.64

$201.40

$227.58

$344.39

$723.98

 

96000

537

Both

Both

Std

 

 

Cyanine3

[Cy3]

5', Int

563

 

 

$119.10

$150.30

$233.70

$286.20

$480.00

$880.00

 

150000

550

DNA

T

Std

 

 

Cyanine3 (ester)

[Cy3es]

5', Int

563

 

 

$119.10

$150.30

$233.70

$286.20

$480.00

$880.00

 

150000

550

DNA

T

Non

 

 

Alexa Fluor 555

[Alexa555]

5', 3', Int

565

 

 

$692.18

$692.18

$1,787.16

$2,940.44

$7,351.10

 

 

150000

555

DNA

T

Std

 

 

Alexa Fluor 546

[Alexa546]

5', 3', Int

573

 

 

$397.50

$397.50

$598.90

$671.67

$1,037.21

$6,095.00

 

104000

556

DNA

T

Std

 

 

ATTO 550

[ATTO550]

5', 3', Int

576

 

 

$217.30

$289.38

$400.68

$495.44

$761.29

 

 

120000

554

DNA

T

Std

 

 

TAMRA dT

[TAMdT]

5', Int

576

 

 

$165.36

$299.98

$447.32

$735.11

$1,837.78

 

 

90000

544

DNA

T

Std

 

 

Tide Fluor 3

[TF3]

5', 3', Int

578

 

 

$148.40

$148.40

$262.88

$339.20

$848.00

$984.74

 

 

554

DNA

T

Std

 

 

TAMRA

[TAM]

3'

580

 

 

$103.88

$121.90

$185.50

$206.44

$317.21

$826.80

 

89000

556

DNA

Both

Std

 

 

5-Tamra (ester)

[TMR5]

5'

583

 

 

$137.80

$164.30

$265.00

$296.06

$782.44

$1,802.00

 

 

557

DNA

T

Std

 

 

CAL Fluor 590

[CalFluor590]

5'

591

 

 

$371.00

$371.00

$482.30

$917.43

$2,290.93

$3,858.40

 

79000

569

DNA

T

Std

 

 

ATTO 565

[ATTO565]

5', 3', Int

592

 

 

$184.44

$278.78

$373.12

$461.21

$708.93

 

 

120000

563

DNA

T

Std

 

 

ROX

[ROX]

5', 3', Int

602

 

 

$184.44

$184.44

$278.78

$344.39

$528.68

$1,897.40

 

82000

575

DNA

T

Std

 

 

Alexa Fluor 568

[Alexa568]

5', 3', Int

603

 

 

$692.18

$692.18

$1,787.16

$2,940.44

$7,351.10

 

 

91000

578

DNA

T

Std

 

 

Texas Red

[TxRed]

5', 3', Int

603

 

 

$212.00

$256.52

$367.82

$453.95

$697.85

 

 

116000

583

DNA

T

Std

 

 

Cyanine3.5

[Cy35]

5', Int

604

 

 

$183.38

$196.10

$311.64

$564.45

$1,409.80

 

 

116000

591

DNA

T

Std

 

 

CAL Fluor Red 610

[CalFluor610]

5'

610

 

 

$371.00

$371.00

$482.30

$917.43

$2,290.93

$3,858.40

 

108000

590

DNA

T

Std

 

 

Tide Fluor 4

[TF4]

5', 3', Int

610

 

 

$148.40

$148.40

$262.88

$339.20

$848.00

$984.74

 

 

588

DNA

T

Std

 

 

Alexa Fluor 594

[Alexa594]

5', 3', Int

617

 

 

$466.40

$466.40

$710.20

$798.55

$2,647.88

$6,837.00

 

73000

590

DNA

T

Std

 

 

ATTO 590

[ATTO590]

5', 3', Int

624

 

 

$184.44

$278.78

$373.12

$460.20

$708.93

 

 

120000

594

DNA

T

Std

 

 

Alexa Fluor 633

[Alexa633]

5', 3', Int

647

 

 

$692.18

$692.18

$1,787.16

$2,940.44

$7,351.10

 

 

239000

632

DNA

T

Std

 

 

ATTO 633

[ATTO633]

5', 3', Int

657

 

 

$217.30

$289.38

$400.68

$495.44

$761.29

 

 

130000

629

DNA

T

Std

 

 

Cyanine5 (std & ester)

[Cy5]

5'

662

 

 

$113.42

$143.10

$222.60

$247.72

$518.61

$1,378.00

 

250000

646

Both

T

Std

 

 

Alexa Fluor 647

[Alexa647]

5', 3', Int

665

 

 

$318.00

$318.00

$477.00

$534.72

$824.73

 

 

239000

650

DNA

T

Std

 

 

ATTO 647N

[ATTO647N]

5', 3', Int

669

 

 

$217.30

$289.38

$400.68

$495.44

$761.29

 

 

150000

644

DNA

T

Std

 

 

Tide Fluor 5

[TF5]

5', 3', Int

670

 

 

$148.40

$148.40

$262.88

$339.20

$848.00

$984.74

 

 

656

DNA

T

Std

 

 

ATTO 655

[ATTO655]

5', 3', Int

684

 

 

$161.12

$234.26

$323.30

$614.27

$1,535.68

 

 

125000

663

DNA

T

Std

 

 

Alexa Fluor 660

[Alexa660]

5', 3', Int

690

 

 

$466.40

$466.40

$710.20

$798.55

$1,223.51

$6,837.00

 

132000

663

DNA

T

Std

 

 

ATTO 680

[ATTO680]

5'

698

 

 

$217.30

$289.38

$400.68

$521.52

$1,616.50

 

 

125000

680

DNA

T

Std

 

 

Alexa Fluor 680

[Alexa680]

5', 3', Int

702

 

 

$692.18

$692.18

$1,787.16

$2,940.44

$7,351.10

 

 

184000

679

DNA

T

Std

 

 

Tide Fluor 6

[TF6]

5', 3', Int

702

 

 

$148.40

$148.40

$262.88

$339.20

$848.00

$984.74

 

 

686

DNA

T

Std

 

 

Cyanine5.5

[Cy55]

5'

707

 

 

$195.04

$217.30

$328.60

$312.17

$624.34

$3,286.00

 

209000

688

DNA

T

Std

 

 

ATTO 700

[ATTO700]

5', 3', Int

719

 

 

$161.12

$234.26

$323.30

$614.27

$1,535.68

 

 

120000

700

DNA

T

Std

 

 

Alexa Fluor 700

[Alexa700]

5', 3', Int

723

 

 

$692.18

$692.18

$1,787.16

$2,940.44

$7,351.10

 

 

192000

702

DNA

T

Std

 

 

ATTO 740

[ATTO740]

5', 3', Int

764

 

 

$153.70

$222.60

$307.40

 

 

 

 

120000

740

DNA

T

Std

 

 

Alexa Fluor 750

[Alexa750]

5', 3', Int

775

 

 

$466.40

$466.40

$710.20

$798.55

$1,223.51

 

 

240000

749

DNA

T

Std

 

 

Tide Fluor 7

[TF7]

5', 3', Int

775

 

 

$148.40

$148.40

$262.88

$339.20

$848.00

$984.74

 

 

756

DNA

T

Std

 

 

Tide Fluor 8

[TF8]

5', 3', Int

808

 

 

$148.40

$148.40

$262.88

$339.20

$848.00

$984.74

 

 

787

DNA

T

Std

 

 

Quenchers

 

Pricing

 

Additional Information

 

Modification

Designator

Positions allowed

N/A

 

25 nmole price

50 nmole price

250 nmole price

1 mole price

2 mole price

5 mole price

10 mole price

 

Extinction coefficient (M-1cm 1)

Max Abs (nm)

DNA or RNA

Tubes or Plates

Std or non-std

Notes

 

BBQ650

[BBQ650]

5', 3'

 

 

 

$272.69

$272.69

$311.64

$623.28

$1,558.20

 

 

33000

650

DNA

T

Std

 

 

BHQ1

[BHQ1]

5', 3'

 

 

 

$116.60

$153.70

$222.60

$380.65

$1,065.30

$2,120.00

 

34000

534

DNA

T

Std

 

 

BHQ1 dT

[BHQ1dT]

5', Int

 

 

 

 

$172.78

$267.12

$508.80

$1,272.00

 

 

34000

534

DNA

T

Std

 

 

BHQ2

[BHQ2]

5', 3'

 

 

 

$116.60

$153.70

$222.60

$287.00

$380.65

$2,120.00

 

91000

579

DNA

T

Std

 

 

BHQ2 dT

[BHQ2dT]

5', Int

 

 

 

 

$294.68

$405.98

$735.11

$1,837.78

 

 

91000

579

DNA

T

Std

 

 

Dabcyl STANDARD

[DAB}

3'

 

 

 

$97.52

$121.90

$185.50

$206.44

$396.76

$916.90

 

32000

453

DNA

T

Std

 

 

Dabcyl dT

[DABdT]

5', Int

 

 

 

$302.10

$405.45

$405.45

$731.40

$1,828.50

 

 

32000

478

DNA

T

Std

 

 

TAMRA

[TAM]

5', 3'

 

 

 

$103.88

$121.90

$185.50

$206.44

$317.21

$826.80

 

91000

557

DNA

T

Std

 

 

Tide Quencher 1

[TQ1]

3'

 

 

 

$48.76

$61.48

$122.96

$212.00

$397.50

$673.10

 

20000

490

DNA

T

Std

 

 

Tide Quencher 2

[TQ2]

3'

 

 

 

$48.76

$61.48

$122.96

$212.00

$397.50

$673.10

 

21000

515

DNA

T

Std

 

 

Tide Quencher 3

[TQ3]

3'

 

 

 

$48.76

$61.48

$122.96

$212.00

$397.50

$673.10

 

22000

570

DNA

T

Std

 

 

Tide Quencher 5

[TQ5]

3'

 

 

 

$48.76

$61.48

$122.96

$212.00

$397.50

$673.10

 

24000

670

DNA

T

Std

 

 

Attachment Linker Mods

 

Pricing

 

Additional Information

 

Modification

Designator

Positions allowed

N/A

 

25 nmole

50 nmole

250 nmole

1 mole

2 mole

5 mole

10 mole

 

N/A

N/A

DNA or RNA

Tubes or Plates

Std or non-std

Notes

 

Amino Modifier C12

[AmC12]

5'

 

 

$66.78

$66.78

$85.86

$127.20

$145.01

$222.55

$514.10

 

 

 

DNA

Both

Std

 

 

Amino Modifier C3

[AmC3]

5', 3'

 

 

 

$111.30

$111.30

$155.82

$281.96

$704.90

 

 

 

 

DNA

T

Std

 

 

Amino Modifier C6

[AmC6]

5'

 

 

$15.90

$29.68

$39.22

$66.78

$74.52

$201.40

$243.80

 

 

 

Both

Both

Std

 

 

Amino Modifier C6-dT

[AmC6dT]

5', Int

 

 

 

$138.86

$167.48

$251.22

$310.16

$476.31

$1,001.70

 

 

 

Both

Both

Std

 

 

Amino Modifier C7

[AmC7]

Int, 3'

 

 

 

$26.50

$26.50

$42.40

$80.56

$201.40

$265.00

 

 

 

Both

Both

Std

 

 

Uni-Link AminoModifier

[AmUni]

5', Int

 

 

 

$83.74

$106.00

$161.12

$201.40

$307.14

$645.54

 

 

 

DNA

Both

Std

 

 

i3Thiodl

[i3Thiodl]

5', Int

 

 

 

 

$278.78

$1,250.80

 

 

 

 

 

 

DNA

T

Std

 

 

Thiol Modifier C6 S-S

[ThiolC6]

5', Int

 

 

 

$153.70

$153.70

$238.50

$477.00

$1,192.50

$916.90

 

 

 

DNA

T

Std

 

 

Thiol Mod C3 S-S

[ThiolC3]

3'

 

 

 

$121.90

$121.90

$185.50

$477.00

$1,192.50

$916.90

 

 

 

DNA

T

Std

 

 

Phosphate

[PHO]

5', 3'

 

 

$24.38

$24.38

$30.74

$55.12

$62.43

$94.66

$223.13

 

 

 

Both

Both

Std

 

 

Non-flourescent labels

 

Pricing

 

Additional Information

 

Modification

Designator

Positions allowed

N/A

 

25 nmole

50 nmole

250 nmole

1 mole

2 mole

5 mole

10 mole

 

N/A

N/A

DNA or RNA

Tubes or Plates

Std or non-std

Notes

 

Biotin

[BIO]

5', 3'

 

 

 

$56.18

$66.78

$128.26

$158.10

$232.62

$467.46

 

 

 

Both

Both

Std

 

 

Biotin PC (Photocleavable)

[BioPC]

5'

 

 

 

$161.12

$161.12

$306.34

 

 

$1,526.40

 

 

 

DNA

T

Std

 

 

Biotin-dT

[BIOdT]

5', Int

 

 

 

$212.00

$212.00

$339.20

$362.52

$692.32

$1,696.00

 

 

 

DNA

Both

Std

 

 

Biotin-ON

[BioON]

5', Int

 

 

 

$61.48

$78.44

$128.26

$231.61

$579.03

$640.24

 

 

 

Both

T

Std

 

 

Biotin-TEG STD (5' or 3')

[BIOTEG]

5', 3'

 

 

 

$97.52

$121.90

$159.00

$179.25

$317.21

$736.70

 

 

 

Both

Both

Std

 

 

Biotin-TEG (internal)

[BIOTEGi]

Int

 

 

 

$56.18

$56.18

$111.30

$201.40

$503.50

$556.50

 

 

 

Both

Both

Std

 

 

Digoxigenin (ester)

[DIG]

5', 3', Int

 

 

 

$143.10

$143.10

$212.00

 

 

$1,725.15

 

 

 

DNA

T

Std

 

 

DNP (2,4-dinitrophenyl)

[DNP]

5', Int

 

 

 

$21.20

$26.50

$47.70

 

 

$190.80

 

 

 

DNA

T

Std

 

 

Modified Bases, Spacers, Miscellaneous

 

Pricing

 

Additional Information

 

Modification

Designator

Positions allowed

N/A

 

25 nmole

50 nmole

250 nmole

1 mole

2 mole

5 mole

10 mole

 

N/A

N/A

DNA or RNA

Tubes or Plates

Std or non-std

Notes

 

23ddC

[23ddC]

3'

 

 

 

$95.40

$95.40

$190.80

 

 

$975.20

 

 

 

DNA

T

Std

 

 

5-Methyl dC

[5MedC]

5', 3', Int

 

 

 

$44.52

$55.65

$83.48

 

 

$625.93

 

 

 

DNA

T

Std

 

 

Acrydite

[5Acrd]

5'

 

 

 

$89.04

$111.30

$167.48

$334.96

$503.50

$667.80

 

 

 

DNA

T

Std

 

 

Cholesteryl-TEG

[CholTEG]

5', Int

 

 

 

$97.52

$97.52

$291.50

$583.00

$1,457.50

$1,484.00

 

 

 

Both

T

Std

 

 

Cholesteryl

[Chol]

3'

 

 

 

$97.52

$97.52

$291.50

$583.00

$1,457.50

$1,484.00

 

 

 

DNA

T

Std

 

 

5' Dabcyl-dT

[5DabsyldT]

5', Int

 

 

 

 

$164.30

$278.25

 

 

$0.00

 

 

 

DNA

T

Std

 

 

deoxyInosine [I]

[I]

5', Int

 

 

$11.13

$11.13

$13.36

$24.38

$40.18

$53.37

$99.64

 

 

 

Both

Both

Std

 

 

deoxyUridine [U]

[U]

5', Int

 

 

$11.13

$11.13

$13.36

$24.38

$39.27

$53.37

$99.64

 

 

 

Both

Both

Std

 

 

dP + dK mixture

[dPdK]

5', Int

 

 

 

$205.64

$205.64

$328.60

 

 

$1,962.06

 

 

 

DNA

T

Std

 

 

dT-5' (reversed base)

[dTrev]

3'

 

 

 

$59.55

$71.02

$108.99

$137.80

$238.50

$445.20

 

 

 

DNA

T

Std

 

 

pdC

[pdC]

5', Int

 

 

$11.13

$11.13

$15.37

$24.38

 

 

$99.64

 

 

 

DNA

T

Std

 

 

pdU

[pdU]

5', Int

 

 

$11.13

$11.13

$15.37

$24.38

 

 

$99.64

 

 

 

DNA

T

Std

 

 

Phosphorothioation
(PTO Bond)

*

Int

 

 

 

$3.71

$3.71

$5.30

$12.72

$25.44

$37.10

 

 

 

DNA

T

Std

 

 

dSpacer

[Spd]

5', Int

 

 

 

$94.34

$111.30

$167.48

$206.44

$317.21

$667.80

 

 

 

DNA

T

Std

 

 

Spacer C18

[SP18]

5', Int

 

 

 

$50.88

$61.48

$99.64

$123.86

$190.32

$400.68

 

 

 

DNA

T

Std

 

 

Spacer C3

[SpC3]

5', Int

 

 

 

$55.12

$66.78

$103.88

$116.81

$159.11

$365.70

 

 

 

DNA

Both

Std

 

 

Spacer C9

[SpC9]

5', Int

 

 

 

$68.90

$73.14

$103.88

 

 

$365.70

 

 

 

DNA

T

Std

 

 

TINA

[TINA]

5'

 

 

 

$55.12

$67.84

$116.60

$233.20

$477.00

$0.00

 

 

 

DNA

T

Std

 

 

2'-Fluoro-A

[2FlA]

5', Int

 

 

$23.32

$43.73

$43.73

$66.46

 

 

$338.14

 

 

 

RNA

T

Std

 

 

2'-Fluoro-C

[2FlC]

5', Int

 

 

$23.32

$43.73

$43.73

$66.46

 

 

$338.14

 

 

 

RNA

T

Std

 

 

2'-Fluoro-G

[2FlG]

5', Int

 

 

$23.32

$43.73

$43.73

$66.46

 

 

$338.14

 

 

 

RNA

T

Std

 

 

2'-Fluoro-U

[2FlU]

5', Int

 

 

$23.32

$43.73

$43.73

$66.46

 

 

$338.14

 

 

 

RNA

T

Std

 

 

2'-O-Methyl A

[2OMeA]

5', 3', Int

 

 

 

$10.02

$14.47

$22.26

$44.52

$82.68

$172.78

 

 

 

RNA

T

Std

 

 

2'-O-Methyl C

[2OMeC]

5', 3', Int

 

 

 

$10.02

$14.47

$22.26

$44.52

$82.68

$172.78

 

 

 

RNA

T

Std

 

 

2'-O-Methyl G

[2OMeG]

5', 3', Int

 

 

 

$10.02

$14.47

$22.26

$44.52

$82.68

$172.78

 

 

 

RNA

T

Std

 

 

2'-O-Methyl U

[2OMeU]

5', 3', Int

 

 

 

$10.02

$14.47

$22.26

$44.52

$82.68

$172.78

 

 

 

RNA

T

Std

 

 

2-MethoxyEthoxy A

[2MoeA]

5', 3', Int

 

 

 

$21.20

$27.56

$48.76

$61.48

 

 

 

 

 

RNA

T

Std

 

 

2-MethoxyEthoxy MeC

[2MoeC]

5', 3', Int

 

 

 

$21.20

$27.56

$48.76

$61.48

 

 

 

 

 

RNA

T

Std

 

 

2-MethoxyEthoxy G

[2MoeG]

5', 3', Int

 

 

 

$21.20

$27.56

$48.76

$61.48

 

 

 

 

 

RNA

T

Std

 

 

2-MethoxyEthoxy T

[2MoeT]

5', 3', Int

 

 

 

$21.20

$27.56

$48.76

$61.48

 

 

 

 

 

RNA

T

Std

 

 

Click Chemistry

 

Pricing

 

Additional Information

 

Modification

Designator

Positions allowed

N/A

 

25 nmole

50 nmole

250 nmole

1 mole

2 mole

5 mole

10 mole

 

N/A

N/A

DNA or RNA

Tubes or Plates

Std or non-std

Notes

 

Azide

[Azide]

5', 3', Int

 

 

 

$116.60

$148.40

$212.00

 

 

$1,484.00

 

 

 

DNA

T

Std

 

 

Hexynyl

[Hexynyl]

5', 3', Int

 

 

 

$125.08

$155.82

$237.44

 

 

$943.40

 

 

 

DNA

T

Std

 

 

Mixed/Degenerate Bases (Wobbles)

 

Pricing

 

Additional Information

 

Modification

Designator

Positions allowed

N/A

 

25 nmole

50 nmole

250 nmole

1 mole

2 mole

5 mole

10 mole

 

N/A

N/A

DNA or RNA

Tubes or Plates

Std or non-std

Notes

 

Machine-Mixed Wobble

See below

5', 3', Int

 

 

Standard base price

Standard base price

Standard base price

Standard base price

Standard base price

Standard base price

Standard base price

 

 

 

Both

Both

Std

 

 

Hand-Mixed Wobble

[%-%-%-%]

5', 3', Int

 

 

$8.48

$8.48

$8.48

$10.60

$21.20

$53.00

$100.70

 

 

 

Both

Both

Std

User defined

 

List of Wobble Bases

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Both

Both

Std

 

 

N (A+C+G+T)

N

5', 3', Int

 

 

 

 

 

 

 

 

 

 

 

 

Both

Both

Std

N = (A, 25%; C, 25%; G, 25%; T, 25%)

 

B (C+G+T)

B

5', 3', Int

 

 

 

 

 

 

 

 

 

 

 

 

Both

Both

Std

B = (C, 33.3%; G, 33.3%; T, 33.3%)

 

D (A+G+T)

D

5', 3', Int

 

 

 

 

 

 

 

 

 

 

 

 

Both

Both

Std

D = (A-33.3%, G-33.3%, T-33.3%)

 

H (A+C+T)

H

5', 3', Int

 

 

 

 

 

 

 

 

 

 

 

 

Both

Both

Std

H = (A, 33.3%; C, 33.3%; T, 33.3%)

 

V (A+C+G)

V

5', 3', Int

 

 

 

 

 

 

 

 

 

 

 

 

Both

Both

Std

V = (A, 33.3%; C, 33.3%; G, 33.3%)

 

K (G+T)

K

5', 3', Int

 

 

 

 

 

 

 

 

 

 

 

 

Both

Both

Std

K = (G, 50%; T, 50%)

 

M (A+C)

M

5', 3', Int

 

 

 

 

 

 

 

 

 

 

 

 

Both

Both

Std

M = (A, 50%; C, 50%)

 

R (A+G)(purines)

R

5', 3', Int

 

 

 

 

 

 

 

 

 

 

 

 

Both

Both

Std

R = (A, 50%; G, 50%)

 

S (C+G)(strong bonds)

S

5', 3', Int

 

 

 

 

 

 

 

 

 

 

 

 

Both

Both

Std

S = (C, 50%; G, 50%)

 

W (A+T)(weak bonds)

W

5', 3', Int

 

 

 

 

 

 

 

 

 

 

 

 

Both

Both

Std

W = (A, 50%; T, 50%)

 

Y (C+T)(pyrimidines)

Y

5', 3', Int

 

 

 

 

 

 

 

 

 

 

 

 

Both

Both

Std

Y = (C, 50%; T, 50%)

 


More Information

Eurofins Genomics offers many more modifications in addition to the standard portfolio. Non-standard modifications are ordered as needed, which adds 1-3 days to the turnaround time.  Below is a list of non-standard modifications. If you do not see the modification that you are looking for, contact us! Our chemists are always up for a challenge.

How to order non-standard modifications

If you would like to order a non-standard modification, contact us at GenomicsSupport@genomics.eurofins-info.com. Most non-standard modifications cannot be entered on the order pages, but we can handle these requests manually.

 

Attachment Mods

Amino, thiol, acrydite, and phosphate groups incorporated during synthesis allow post synthesis reactions for attaching a variety of labels or for coupling the oligo with other molecules.

Modifier
[Legacy Designator]
Availability
Structure
3'-PT-Amino-Modifier C3  [AmC3PT]
Legacy designator: [AmC3-PT]
3'
Amino Modifier C2 dT  [AmC2dT]
Legacy designator:[AmC2-dT]
5', Internal
Am C2-dT
AminoC6 dC  [AmC6dC]
Legacy designator: [AmC6-dC]
5', Internal
Image not available.


DNA Analogs

 

Molecules with similar structure to DNA often readily substitute in the DNA strand for a variety of experimental uses. Modifications in this category include inosine, uridine, wobbles, etc.

Modifier
[Legacy Designator]
Availability
Structure
3-Nitropyrrole [NitPyr]
5', Internal
Nitroyrrole
5-Nitroindole [NitIdl]
Legacy designator: [5-NitIdl]
3'
5-Nitroindole  [5-NitIdl]
Legacy designator: [5-NitIdl]
5', Internal
AP-dC  
Legacy designator: [AP-dC]
5', Internal
Image not available.
dK [dK]
5', Internal
dP  [dP]
3'
dP  [dP]
5', Internal
dP + dK mixture  [dPdK]
5', Internal

Fluorophores

Fluorescent molecules offer a wide variety of applications requiring detection of hybridization including in situ probes, sequencing, and genotyping.

Modifier
[Legacy Designator]
Availability
Structure
6-Carboxyfluorescein  [6Fl]
5', Internal
6-Carboxyrhodamine (ester) [CR6G]
5', 3', Internal
Cyanine3 (ester)
Legacy designator: [Cyanine3es]
3'
Image not available.
Cyanine3.5 (ester)
Legacy designator:[Cyanine35es]
3'
Image not available.
Cyanine5 (ester)
Legacy designator: [Cyanine5es]
3'
Image not available.
DY682 (replaces IRD700)  [DY682]
5', 3'
Image not available.
DY782 (replaces IRD800)  [DY782]
5'
Image not available.
Tamra (ester) - 5-isomer  [TMR-5]
5', 3', Internal
Tide Quencher 2 ester  [TQ2es]
5', 3', Internal
Image not available.


Mixed Bases

 

Standard bases used in combination to create a base comprised of a mixture of 2-4 bases (e.g. A/C or A/C/G). This category includes IUB Wobbles and custom wobbles.

Modifier
[Legacy Designator]
Availability
Structure
Mix-1 MG
[Mix-1]
5', Internal
Image not available.


Quenchers

Quenchers are most commonly paired with specific fluorophores and are chosen based on their ability to absorb energy at the emission wavelength of the fluorophore.

Modifier
[Legacy Designator]
Availability
Structure
5-Dabcyl  [DAB5]
Legacy designator: [5-Dabcyl]
5'
QSY 7 (ester)   [QSY7]
5', 3', Internal
Tide Quencher 4  [TQ4]
3'
Image not available.

 

Modified Bases

Chemically modified bases can be used for structural studies and enhanced binding. This category includes Br-dU, 5-methyl dC, 5-iodo dU, 2-aminopurine, etc.

Modifier
[Legacy Designator]
Availability
Structure
2-Aminopurine  [2AmPur]
5', Internal
5-Bromo dU  [5BrdU]
Legacy designator: [5Br-dU]
3'
5-Bromo-dC [5BrdC]
Legacy designator: [5Br-dC]
5', Internal
5-Bromo-dU  [5BrdU]
Legacy designator:[5Br-dU]
5', Internal
5-Iodo-dU  [5IdU]
Legacy designator: [5I-dU]
5', Internal
O6-phenyl-dI  [6phnldI]
Legacy designator: [6phnl-dI]
5', Internal
Pyrrolo-dC  [PyrlodC]
Legacy designator: [Pyrlo-dC]
5', Internal


RNA Analogs

RNA analogs are useful for creating the chimeric DNA/RNA oligos commonly used in anti-sense studies.

Modifier
[Designator]
Availability
Structure
5'OH-Methyl-C  [5HOMedC]
5', Internal
Image not available.
Pyrrolo-RNA-C 
Legacy designator: [Pyrrolo-rC]
5', Internal
Image not available.
Ribo A  [rA]
5', Internal
Image not available.
Ribo A  [rA]
3'
Image not available.
Ribo C  [rC]
3'
Image not available.
Ribo C  [rC]
5', Internal
Image not available.
Ribo G  [rG]
3'
Image not available.
Ribo G  [rG]
5', Internal
Image not available.
Ribo U  [rU]
5', Internal
Image not available.
Ribo U  [rU]
3'
Image not available.
Ribo-8OxrG
Legacy designator: [8Ox-rG]
5', Internal
Image not available.

 


Miscellaneous

 

Miscellaneous modifications include phosphorothioate backbone modification, digoxigenin labeling, modified bases to prevent extension of the 3' terminus, cholesterol for cell delivery, puromycin (a tRNA mimc), etc.

Modifier
[Designator]
Availability
Structure
3'-dA (chain terminator)
[3-dA]
3'
3'-dC (chain terminator)
[3-dC]
3'
3'-dG (chain terminator)
[3-dG]
3'
3'-dT (chain terminator)
[3-dT]
3'
5-Pyrine Cap
[5-PyrCAP]
5'
Image not available.
Cholesteryl-TEG
[Chols]
3'
Puromycin
[Pmycn]
3'

 

How to order standard modifications

There are two ways to add a modification to a sequence. One, the designator can be entered directly into the sequencing prior to upload, and the system will identify the modification and include it during the sequence validation process. Secondly, each order page contains a dropdown list of available modifications for each position. Please note that designators are case sensitive.

 

How to order non-standard modifications

If you would like to order a non-standard modification, contact us at GenomicsSupport@eurofins.com. Most non-standard modifications cannot be entered on the order pages, but we can handle these requests manually.

Independent of the intended application, some modifications require further purification and/or a higher scale. Any inter-dependencies are represented on the ordering page so it is clear and transparent for customers while placing orders.

Standard Oligonucleotide Modifications for custom DNA and RNA synthesis

Eurofins Genomics offers a wide variety of modifications for both DNA and RNA oligos to meet the needs of virtually any project. Modifications that are regularly stocked in-house are considered the "standard modifications portfolio." Standard modifications are listed below.

Non-standard modifications

Non-standard modifications refer to any modification that is not listed in the standard portfolio. Typically, non-standard modifications derive from a.) custom modifications supplied by the customer, b.) special requests from customers for modifications not listed in the standard portfolio, and c.) modifications that we have prior expertise with but may not keep in stock due to the infrequency of orders. Eurofins Genomics can accommodate requests for non-standard modifications. We understand that much of science revolves around experimentation and new needs arise from new techniques.  Do not see a modification you want? Contact us to request a modification.

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Specifications

Pricing

Modification / Category

Designator

5'

Int

3'

DNA or RNA

Tubes or Plates

Max Abs (nm)

Max Em (nm)

Extinction coefficient (M-1cm 1)

50 nmole

250 nmole

1 mole

2 mole

5 mole

10 mole

Notes

Fluorophores

Alexa Fluor 350

[Alexa350]

DNA

T

346

424

19000

$692.18

$692.18

$1,787.16

$2,940.44

$7,351.10

 

Alternative to AMCA

CF 405S succinimidyl ester (CF405SN)

[CF405SN]

DNA

T

404

431

33000

 

$278.78

$1,250.80

 

 

 

--

Tide Fluor 1

[TF1]

DNA

T

341

447

 

$148.40

$148.40

$262.88

$339.20

$848.00

$1,454.32

 

ATTO 390

[ATTO390]

DNA

T

390

479

24000

$161.12

$234.26

$323.30

$584.06

$1,535.68

 

 

5-FAM

[5FAM]

 

 

Both

T

492

518

 

$58.30

$74.20

$153.70

$167.48

$243.80

$556.50

Alternative to CY2, DY-495, ATTO 495

Alexa Fluor 488

[Alexa488]

DNA

T

496

519

71000

$318.00

$318.00

$477.00

$539.54

$824.73

 

 

Fluorescein

[FL]

 

DNA

T

495

520

83000

$68.90

$85.86

$185.50

$262.88

$479.12

 

Alternative to DY-495, ATTO 495

6-FAM

[FAM]

 

Both

Both

495

521

75000

$72.08

$90.10

$195.04

$253.34

$362.52

$556.50

 

Fluorescein dT

[FLUdT]

 

DNA

T

494

522

75000

$212.00

$238.50

$339.20

$380.65

$727.05

$1,696.00

Alternative to DY-495, ATTO 495

Tide Fluor 2

[TF2]

DNA

T

499

522

 

$148.40

$148.40

$262.88

$339.20

$848.00

$984.74

 

ATTO 488

[ATTO488]

DNA

T

501

523

90000

$217.30

$289.38

$400.68

$495.44

$761.29

 

Alternative to Cy2

Oregon Green 488

[OG488]

DNA

T

496

524

76000

$397.50

$397.50

$598.90

$676.70

$1,037.21

$6,095.00

Alternative to Cy2

TET

[TET]

 

 

Both

Both

519

539

86000

$79.50

$99.64

$201.40

$402.80

$1,007.00

$795.00

Alternative to CAL Fluor Gold 540

CAL Fluor Gold 540

[CalFluor540]

 

 

DNA

T

522

543

81100

$397.50

$397.50

$598.90

$676.70

$1,037.21

$6,095.00

Alternative to 81100

JOE

[JOE]

DNA

T

520

548

73000

$217.30

$217.30

$328.60

$0.00

$0.00

$7,844.00

Alternative to CAL Fluor Gold 540, Rhodamine 6G

Yakima Yellow

[YAKYE]

 

 

DNA

T

530

549

 

$83.74

$106.00

$213.48

$280.90

$561.80

$1,123.60

Alternative to VIC, CAL Fluor 560

Alexa Fluor 532

[Alexa532]

DNA

T

532

553

81000

$397.50

$397.50

$598.90

$676.70

$1,037.21

$6,095.00

 

ATTO 532

[ATTO532]

DNA

T

532

553

115000

$217.30

$289.38

$400.68

$497.46

$761.29

 

 

HEX

[HEX]

 

 

Both

Both

537

556

96000

$79.50

$99.64

$201.40

$227.58

$344.39

$723.98

Alternative to VIC, CAL Fluor 560, SIMA

Cyanine3

[Cy3]

 

DNA

T

550

563

150000

$119.10

$150.30

$233.70

$286.20

$480.00

$880.00

 

Cyanine3 (ester)

[Cy3es]

 

DNA

T

550

563

150000

$119.10

$150.30

$233.70

$286.20

$480.00

$880.00

 

Alexa Fluor 555

[Alexa555]

DNA

T

555

565

150000

$692.18

$692.18

$1,787.16

$2,940.44

$7,351.10

 

Alternative to Cy3, TRITC & TMR, Alexa Fluor 546

Alexa Fluor 546

[Alexa546]

DNA

T

556

573

104000

$397.50

$397.50

$598.90

$671.67

$1,037.21

$6,095.00

 

ATTO 550

[ATTO550]

DNA

T

554

576

120000

$217.30

$289.38

$400.68

$495.44

$761.29

 

Alternative to NED, Cy3, Rhodamine B & 6G

TAMRA dT

[TAMdT]

 

DNA

T

544

576

90000

$165.36

$299.98

$447.32

$735.11

$1,837.78

 

 

Tide Fluor 3

[TF3]

DNA

T

554

578

 

$148.40

$148.40

$262.88

$339.20

$848.00

$984.74

 

TAMRA

[TAM]

 

 

DNA

Both

556

580

89000

$103.88

$121.90

$185.50

$206.44

$317.21

$826.80

Alternative to Rhodamine 6G, Rhodamine B, CAL Fluor 590

5-Tamra (ester)

[TMR5]

 

 

DNA

T

557

583

 

$137.80

$164.30

$265.00

$296.06

$782.44

$1,802.00

 

CAL Fluor 590

[CalFluor590]

 

 

DNA

T

569

591

79000

$371.00

$371.00

$482.30

$917.43

$2,290.93

$3,858.40

 

ATTO 565

[ATTO565]

DNA

T

563

592

120000

$184.44

$278.78

$373.12

$461.21

$708.93

 

Alternative to PET, Alexa Fluor 594

ROX

[ROX]

DNA

T

575

602

82000

$184.44

$184.44

$278.78

$344.39

$528.68

$1,897.40

Alternative to Texas Red, Alexa Fluor 594, CAL Fluor Red 610

Alexa Fluor 568

[Alexa568]

DNA

T

578

603

91000

$692.18

$692.18

$1,787.16

$2,940.44

$7,351.10

 

 

Texas Red

[TxRed]

DNA

T

583

603

116000

$212.00

$256.52

$367.82

$453.95

$697.85

 

Alternative to ROX, Alexa Fluor 594

Cyanine3.5

[Cy35]

 

DNA

T

591

604

116000

$183.38

$196.10

$311.64

$564.45

$1,409.80

 

Alternative to Alexa Fluor 594, CAL Fluor Red 610

CAL Fluor Red 610

[CalFluor610]

 

 

DNA

T

590

610

108000

$371.00

$371.00

$482.30

$917.43

$2,290.93

$3,858.40

Alternative to Texas Red, ROX, Alexa Fluor 594

Tide Fluor 4

[TF4]

DNA

T

588

610

 

$148.40

$148.40

$262.88

$339.20

$848.00

$984.74

 

Alexa Fluor 594

[Alexa594]

DNA

T

590

617

73000

$466.40

$466.40

$710.20

$798.55

$2,647.88

$6,837.00

Alternative to ATTO 594, CAL Fluor Red 610

ATTO 590

[ATTO590]

DNA

T

594

624

120000

$184.44

$278.78

$373.12

$460.20

$708.93

 

 

Alexa Fluor 633

[Alexa633]

DNA

T

632

647

239000

$692.18

$692.18

$1,787.16

$2,940.44

$7,351.10

 

 

ATTO 633

[ATTO633]

DNA

T

629

657

130000

$217.30

$289.38

$400.68

$495.44

$761.29

 

Alternative to LIZ, Alexa Fluor 633

Cyanine5 (std & ester)

[Cy5]

 

 

Both

T

646

662

250000

$113.42

$143.10

$222.60

$247.72

$518.61

$1,378.00

Alternative to Quasar 670, TYE 655, TYE 665

Alexa Fluor 647

[Alexa647]

DNA

T

650

665

239000

$318.00

$318.00

$477.00

$534.72

$824.73

 

Alternative to Cy5, Quasar 670

ATTO 647N

[ATTO647N]

DNA

T

644

669

150000

$217.30

$289.38

$400.68

$495.44

$761.29

 

Alternative to Cy5, Quasar 670

Tide Fluor 5

[TF5]

DNA

T

656

670

 

$148.40

$148.40

$262.88

$339.20

$848.00

$984.74

 

ATTO 655

[ATTO655]

DNA

T

663

684

125000

$161.12

$234.26

$323.30

$614.27

$1,535.68

 

 

Alexa Fluor 660

[Alexa660]

DNA

T

663

690

132000

$466.40

$466.40

$710.20

$798.55

$1,223.51

$6,837.00

 

ATTO 680

[ATTO680]

 

 

DNA

T

680

698

125000

$217.30

$289.38

$400.68

$521.52

$1,616.50

 

 

Alexa Fluor 680

[Alexa680]

DNA

T

679

702

184000

$692.18

$692.18

$1,787.16

$2,940.44

$7,351.10

 

Alternative to Alexa Fluor 680, Alexa Fluor 700

Tide Fluor 6

[TF6]

DNA

T

686

702

 

$148.40

$148.40

$262.88

$339.20

$848.00

$984.74

 

Cyanine5.5

[Cy55]

 

 

DNA

T

688

707

209000

$195.04

$217.30

$328.60

$312.17

$624.34

$3,286.00

Alternative to Alexa Fluor 680, TYE 705

ATTO 700

[ATTO700]

DNA

T

700

719

120000

$161.12

$234.26

$323.30

$614.27

$1,535.68

 

 

Alexa Fluor 700

[Alexa700]

DNA

T

702

723

192000

$692.18

$692.18

$1,787.16

$2,940.44

$7,351.10

 

Alternative to IRDye 700, Quasar 705

ATTO 740

[ATTO740]

DNA

T

740

764

120000

$153.70

$222.60

$307.40

 

 

 

Alternative to Cy7, Alexa Fluor 740

Alexa Fluor 750

[Alexa750]

DNA

T

749

775

240000

$466.40

$466.40

$710.20

$798.55

$1,223.51

 

 

Tide Fluor 7

[TF7]

DNA

T

756

775

 

$148.40

$148.40

$262.88

$339.20

$848.00

$984.74

 

Tide Fluor 8

[TF8]

DNA

T

787

808

 

$148.40

$148.40

$262.88

$339.20

$848.00

$984.74

 

Quenchers

Designator

5'

Int

3'

DNA or RNA

Tubes or Plates

Max Abs (nm)

Max Em (nm)

Extinction coefficient (M-1cm 1)

50 nmole

250 nmole

1 mole

2 mole

5 mole

10 mole

Notes

BBQ650

[BBQ650]

 

DNA

T

650

n/a

33000

$272.69

$272.69

$311.64

$623.28

$1,558.20

 

 

BHQ1

[BHQ1]

 

DNA

T

534

n/a

34000

$116.60

$153.70

$222.60

$380.65

$1,065.30

$2,120.00

 

BHQ1 dT

[BHQ1dT]

 

DNA

T

534

n/a

34000

 

$172.78

$267.12

$508.80

$1,272.00

 

 

BHQ2

[BHQ2]

 

DNA

T

579

n/a

91000

$116.60

$153.70

$222.60

$287.00

$380.65

$2,120.00

 

BHQ2 dT

[BHQ2dT]

 

DNA

T

579

n/a

91000

 

$294.68

$405.98

$735.11

$1,837.78

 

 

Dabcyl STANDARD

[DAB}

 

 

DNA

T

453

n/a

32000

$97.52

$121.90

$185.50

$206.44

$396.76

$916.90

 

Dabcyl dT

[DABdT]

 

DNA

T

478

n/a

32000

$302.10

$405.45

$405.45

$731.40

$1,828.50

 

 

TAMRA

[TAM]

 

DNA

T

557

n/a

91000

$103.88

$121.90

$185.50

$206.44

$317.21

$826.80

 

Tide Quencher 1

[TQ1]

 

 

DNA

T

490

n/a

20000

$48.76

$61.48

$122.96

$212.00

$397.50

$673.10

 

Tide Quencher 2

[TQ2]

 

 

DNA

T

515

n/a

21000

$48.76

$61.48

$122.96

$212.00

$397.50

$673.10

 

Tide Quencher 3

[TQ3]

 

 

DNA

T

570

n/a

22000

$48.76

$61.48

$122.96

$212.00

$397.50

$673.10

 

Tide Quencher 5

[TQ5]

 

 

DNA

T

670

n/a

24000

$48.76

$61.48

$122.96

$212.00

$397.50

$673.10

 

 

Specifications

Pricing

Modification / Category

Designator

5'

Int

3'

DNA or RNA

Tubes or Plates

25 nmole

50 nmole

250 nmole

1 mole

2 mole

5 mole

10 mole

Notes

Mixed/Degenerate Bases (Wobbles)

Machine-Mixed Wobble

See below

Both

Both

Standard base price

Standard base price

Standard base price

Standard base price

Standard base price

Standard base price

Standard base price

 

Hand-Mixed Wobble

[%-%-%-%]

Both

Both

$8.48

$8.48

$8.48

$10.60

$21.20

$53.00

$100.70

User defined

List of Wobble Bases

 

 

 

 

 

 

 

 

 

 

 

 

 

 

N (A+C+G+T)

N

 

 

 

 

 

 

 

 

 

 

 

 

N = (A, 25%; C, 25%; G, 25%; T, 25%)

B (C+G+T)

B

 

 

 

 

 

 

 

 

 

 

 

 

B = (C, 33.3%; G, 33.3%; T, 33.3%)

D (A+G+T)

D

 

 

 

 

 

 

 

 

 

 

 

 

D = (A-33.3%, G-33.3%, T-33.3%)

H (A+C+T)

H

 

 

 

 

 

 

 

 

 

 

 

 

H = (A, 33.3%; C, 33.3%; T, 33.3%)

V (A+C+G)

V

 

 

 

 

 

 

 

 

 

 

 

 

V = (A, 33.3%; C, 33.3%; G, 33.3%)

K (G+T)

K

 

 

 

 

 

 

 

 

 

 

 

 

K = (G, 50%; T, 50%)

M (A+C)

M

 

 

 

 

 

 

 

 

 

 

 

 

M = (A, 50%; C, 50%)

R (A+G)(purines)

R

 

 

 

 

 

 

 

 

 

 

 

 

R = (A, 50%; G, 50%)

S (C+G)(strong bonds)

S

 

 

 

 

 

 

 

 

 

 

 

 

S = (C, 50%; G, 50%)

W (A+T)(weak bonds)

W

 

 

 

 

 

 

 

 

 

 

 

 

W = (A, 50%; T, 50%)

Y (C+T)(pyrimidines)

Y

 

 

 

 

 

 

 

 

 

 

 

 

Y = (C, 50%; T, 50%)

Attachment Linker Mods

Designator

5'

Int

3'

DNA or RNA

Tubes or Plates

25 nmole

50 nmole

250 nmole

1 mole

2 mole

5 mole

10 mole

Notes

Amino Modifier C12

[AmC12]

 

 

DNA

Both

$66.78

$66.78

$85.86

$127.20

$145.01

$222.55

$514.10

 

Amino Modifier C3

[AmC3]

 

DNA

T

 

$111.30

$111.30

$155.82

$281.96

$704.90

 

 

Amino Modifier C6

[AmC6]

 

 

Both

Both

$15.90

$29.68

$39.22

$66.78

$74.52

$201.40

$243.80

 

Amino Modifier C6-dT

[AmC6dT]

 

Both

Both

 

$138.86

$167.48

$251.22

$310.16

$476.31

$1,001.70

 

Amino Modifier C7

[AmC7]

 

Both

Both

 

$26.50

$26.50

$42.40

$80.56

$201.40

$265.00

 

Uni-Link AminoModifier

[AmUni]

 

DNA

Both

 

$83.74

$106.00

$161.12

$201.40

$307.14

$645.54

 

i3Thiodl

[i3Thiodl]

 

DNA

T

 

 

$278.78

$1,250.80

 

 

 

 

Thiol Modifier C6 S-S

[ThiolC6]

 

DNA

T

 

$153.70

$153.70

$238.50

$477.00

$1,192.50

$916.90

 

Thiol Mod C3 S-S

[ThiolC3]

 

 

DNA

T

 

$121.90

$121.90

$185.50

$477.00

$1,192.50

$916.90

 

Phosphate

[PHO]

 

Both

Both

$24.38

$24.38

$30.74

$55.12

$62.43

$94.66

$223.13

 

Non-flourescent labels

Designator

5'

Int

3'

DNA or RNA

Tubes or Plates

25 nmole

50 nmole

250 nmole

1 mole

2 mole

5 mole

10 mole

Notes

Biotin

[BIO]

 

Both

Both

 

$56.18

$66.78

$128.26

$158.10

$232.62

$467.46

 

Biotin PC (Photocleavable)

[BioPC]

 

 

DNA

T

 

$161.12

$161.12

$306.34

 

 

$1,526.40

 

Biotin-dT

[BIOdT]

 

DNA

Both

 

$212.00

$212.00

$339.20

$362.52

$692.32

$1,696.00

 

Biotin-ON

[BioON]

 

Both

T

 

$61.48

$78.44

$128.26

$231.61

$579.03

$640.24

 

Biotin-TEG STD (5' or 3')

[BIOTEG]

 

Both

Both

 

$97.52

$121.90

$159.00

$179.25

$317.21

$736.70

 

Biotin-TEG (internal)

[BIOTEGi]

 

 

Both

Both

 

$56.18

$56.18

$111.30

$201.40

$503.50

$556.50

 

Digoxigenin (ester)

[DIG]

DNA

T

 

$143.10

$143.10

$212.00

 

 

$1,725.15

 

DNP (2,4-dinitrophenyl)

[DNP]

 

DNA

T

 

$21.20

$26.50

$47.70

 

 

$190.80

 

Modified Bases, Spacers, Miscellaneous

Designator

5'

Int

3'

DNA or RNA

Tubes or Plates

25 nmole

50 nmole

250 nmole

1 mole

2 mole

5 mole

10 mole

Notes

23ddC

[23ddC]

 

 

DNA

T

 

$95.40

$95.40

$190.80

 

 

$975.20

 

5-Methyl dC

[5MedC]

DNA

T

 

$44.52

$55.65

$83.48

 

 

$625.93

 

Acrydite

[5Acrd]

 

 

DNA

T

 

$89.04

$111.30

$167.48

$334.96

$503.50

$667.80

 

Cholesteryl-TEG

[CholTEG]

 

Both

T

 

$97.52

$97.52

$291.50

$583.00

$1,457.50

$1,484.00

 

Cholesteryl

[Chol]

 

 

DNA

T

 

$97.52

$97.52

$291.50

$583.00

$1,457.50

$1,484.00

 

5' Dabcyl-dT

[5DabsyldT]

 

DNA

T

 

 

$164.30

$278.25

 

 

 

 

deoxyInosine [I]

[I]

 

Both

Both

$11.13

$11.13

$13.36

$24.38

$40.18

$53.37

$99.64

 

deoxyUridine [U]

[U]

 

Both

Both

$11.13

$11.13

$13.36

$24.38

$39.27

$53.37

$99.64

 

dP + dK mixture

[dPdK]

 

DNA

T

 

$205.64

$205.64

$328.60

 

 

$1,962.06

 

dT-5' (reversed base)

[dTrev]

 

 

DNA

T

 

$59.55

$71.02

$108.99

$137.80

$238.50

$445.20

 

pdC

[pdC]

 

DNA

T

$11.13

$11.13

$15.37

$24.38

 

 

$99.64

 

pdU

[pdU]

 

DNA

T

$11.13

$11.13

$15.37

$24.38

 

 

$99.64

 

Phosphorothioation
(PTO Bond)

*

 

 

DNA

T

 

$3.71

$3.71

$5.30

$12.72

$25.44

$37.10

 

dSpacer

[Spd]

 

DNA

T

 

$94.34

$111.30

$167.48

$206.44

$317.21

$667.80

 

Spacer C18

[SP18]

 

DNA

T

 

$50.88

$61.48

$99.64

$123.86

$190.32

$400.68

 

Spacer C3

[SpC3]

DNA

Both

 

$55.12

$66.78

$103.88

$116.81

$159.11

$365.70

 

Spacer C9

[SpC9]

 

DNA

T

 

$68.90

$73.14

$103.88

 

 

$365.70

 

TINA

[TINA]

 

 

DNA

T

 

$55.12

$67.84

$116.60

$233.20

$477.00

$0.00

 

2'-Fluoro-A

[2FlA]

 

RNA

T

$23.32

$43.73

$43.73

$66.46

 

 

$338.14

 

2'-Fluoro-C

[2FlC]

 

RNA

T

$23.32

$43.73

$43.73

$66.46

 

 

$338.14

 

2'-Fluoro-G

[2FlG]

 

RNA

T

$23.32

$43.73

$43.73

$66.46

 

 

$338.14

 

2'-Fluoro-U

[2FlU]

 

RNA

T

$23.32

$43.73

$43.73

$66.46

 

 

$338.14

 

2'-O-Methyl A

[2OMeA]

RNA

T

 

$10.02

$14.47

$22.26

$44.52

$82.68

$172.78

 

2'-O-Methyl C

[2OMeC]

RNA

T

 

$10.02

$14.47

$22.26

$44.52

$82.68

$172.78

 

2'-O-Methyl G

[2OMeG]

RNA

T

 

$10.02

$14.47

$22.26

$44.52

$82.68

$172.78

 

2'-O-Methyl U

[2OMeU]

RNA

T

 

$10.02

$14.47

$22.26

$44.52

$82.68

$172.78

 

2-MethoxyEthoxy A

[2MoeA]

RNA

T

 

$21.20

$27.56

$48.76

$61.48

 

 

 

2-MethoxyEthoxy MeC

[2MoeC]

RNA

T

 

$21.20

$27.56

$48.76

$61.48

 

 

 

2-MethoxyEthoxy G

[2MoeG]

RNA

T

 

$21.20

$27.56

$48.76

$61.48

 

 

 

2-MethoxyEthoxy T

[2MoeT]

RNA

T

 

$21.20

$27.56

$48.76

$61.48

 

 

 

Click Chemistry

Designator

5'

Int

3'

DNA or RNA

Tubes or Plates

25 nmole

50 nmole

250 nmole

1 mole

2 mole

5 mole

10 mole

Notes

Azide

[Azide]

DNA

T

 

$116.60

$148.40

$212.00

 

 

$1,484.00

 

Hexynyl

[Hexynyl]

DNA

T

 

$125.08

$155.82

$237.44

 

 

$943.40

 

 

 

Regulated Environments

Our oligos are manufactured in our ISO 9001:2008 and ISO 13485:2003 certified facility in Louisville, Alabama. Eurofins Genomics quality management system is assurance that our oligos and other products and services are suitable for use in your cGMP, ASR, or QS regulation projects. Contact us at 1-800-688-2248 to discuss high throughput modified oligos for your FDA or CLIA regulated projects.

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